About: Influenza and other respiratory virus infections in outpatients with medically attended acute respiratory infection during the 2011-12 influenza season

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About: Influenza and other respiratory virus infections in outpatients with medically attended acute respiratory infection during the 2011-12 influenza season Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Influenza and other respiratory virus infections in outpatients with medically attended acute respiratory infection during the 2011-12 influenza season
Creator	Bullotta, Arlene Moehling, Krissy Wisniewski, Stephen Zimmerman, Richard Thompson, Mark Nowalk, Mary Rinaldo, Charles Gk, Balasubramani
Source	Medline; PMC
abstract	BACKGROUND: Respiratory tract infections are a major cause of outpatient visits, yet only a portion is tested to determine the etiologic organism. Multiplex reverse transcriptase polymerase chain reaction (MRT-PCR) assays for detection of multiple viruses are being used increasingly in clinical settings. METHODS: During January–April 2012, outpatients with acute respiratory illness (≤7 days) were tested for influenza using singleplex RT-PCR (SRT-PCR). A subset was assayed for 18 viruses using MRT-PCR to compare detection of influenza and examine the distribution of viruses and characteristics of patients using multinomial logistic regression. RESULTS: Among 662 participants (6 months–82 years), detection of influenza was similar between the MRT-PCR and SRT-PCR (κ = 0·83). No virus was identified in 267 (40.3%) samples. Commonly detected viruses were human rhinovirus (HRV, 15·4%), coronavirus (CoV, 10·4%), respiratory syncytial virus (RSV, 8·4%), human metapneumovirus (hMPV, 8·3%), and influenza (6%). Co-detections were infrequent (6·9%) and most commonly occurred among those <18 years old. In regression analyses, compared with non-viral illnesses, RSV and hMPV were significantly more frequent in children and less frequent in 18- to 49-year-olds than in those ≥50 years (P = 0·01), fever was more common in hMPV and influenza infections (P = 0·008), nasal congestion was more frequent in CoV, HRV, hMPV, influenza and RSV infections (P = 0·001), and body mass index was higher among those with influenza (P = 0·036). CONCLUSIONS: Using MRT-PCR, a viral etiology was found in three-fifths of patients with medically attended outpatient visits for acute respiratory illness during the influenza season; co-detected viruses were infrequent. Symptoms varied by viral etiology.
has issue date	2014-04-08(xsd:dateTime)
bibo:doi	10.1111/irv.12247
bibo:pmid	24852890
has license	cc-by
sha1sum (hex)	55f79ab7db345d29089af0c330d95292350ba225
schema:url	https://doi.org/10.1111/irv.12247
resource representing a document's title	Influenza and other respiratory virus infections in outpatients with medically attended acute respiratory infection during the 2011-12 influenza season
has PubMed Central identifier	PMC4057994
has PubMed identifier	24852890
schema:publication	Influenza Other Respir Viruses
resource representing a document's body	covid:55f79ab7db345d29089af0c330d95292350ba225#body_text
is schema:about of	named entity 'influenza' named entity 'OUTPATIENTS' named entity 'RESPIRATORY VIRUS' named entity 'INFLUENZA SEASON' named entity 'ACUTE RESPIRATORY INFECTION' named entity 'INFECTIONS' named entity '2011' named entity 'INFLUENZA' named entity 'ATTENDED' named entity 'Influenza' named entity 'Influenza' named entity 'probability distribution' named entity 'dependent variable' named entity 'influenza' named entity 'influenza viruses' named entity 'cough' named entity 'RT-PCR' named entity 'multiple comparisons' named entity 'HRV' named entity 'older adults' named entity 'viruses' named entity 'RSV' named entity 'viruses' named entity 'Co-infection' named entity 'electronic medical record' named entity 'Europe' named entity 'RSV' named entity 'older adults' named entity 'HRV' named entity 'small cell' named entity 'standard deviation' named entity 'virus' named entity 'virus' named entity 'influenza' named entity 'BMI' named entity 'viral infections' named entity 'sore throat' named entity 'influenza' named entity 'respiratory illness' named entity 'ARI' named entity 'sore throat' named entity 'day care' named entity 'influenza' named entity 'respiratory viral infections' named entity 'PCR' named entity 'positive relationship' named entity 'EMR' named entity 'mucosa' named entity 'influenza' named entity 'viruses' named entity 'emergency departments' named entity 'human metapneumovirus' named entity 'zanamivir' named entity 'confidence limits' named entity 'influenza' named entity 'nucleotide sequences' named entity 'virus' named entity 'influenza' named entity 'influenza' named entity 'virus' named entity 'Multinomial regression' named entity 'RSV' named entity 'human rhinovirus' named entity 'health status' named entity 'RSV infection' named entity 'demographic' named entity 'influenza' named entity 'viral infections' named entity 'antivirals' named entity 'HRV' named entity 'influenza' named entity 'influenza' named entity 'cough' named entity 'cough'

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