About: Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam

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About: Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam
Creator	Woolhouse, Mark Simmonds, Peter Baker, Stephen Thwaites, Guy Carrique-Mas, Juan Bonsall, David Van Nguyen, Cuong Bryant, Juliet Ngo, Tue Nguyen, Dung Pham, Anh
source	Medline; PMC
abstract	Rodents and bats are now widely recognised as important sources of zoonotic virus infections in other mammals, including humans. Numerous surveys have expanded our knowledge of diverse viruses in a range of rodent and bat species, including their origins, evolution, and range of hosts. In this study of pegivirus and human hepatitis-related viruses, liver and serum samples from Vietnamese rodents and bats were examined by PCR and sequencing. Nucleic acids homologous to human hepatitis B, C, E viruses were detected in liver samples of 2 (1.3%) of 157 bats, 38 (8.1%), and 14 (3%) of 470 rodents, respectively. Hepacivirus-like viruses were frequently detected (42.7%) in the bamboo rat, Rhizomys pruinosus, while pegivirus RNA was only evident in 2 (0.3%) of 638 rodent serum samples. Complete or near-complete genome sequences of HBV, HEV and pegivirus homologues closely resembled those previously reported from rodents and bats. However, complete coding region sequences of the rodent hepacivirus-like viruses substantially diverged from all of the currently classified variants and potentially represent a new species in the Hepacivirus genus. Of the viruses identified, their routes of transmission and potential to establish zoonoses remain to be determined.
has issue date	2018-02-28(xsd:dateTime)
bibo:doi	10.3390/v10030102
bibo:pmid	29495551
has license	cc-by
sha1sum (hex)	5669349639eae4f58b4fecca26fcc271094c70ba
schema:url	https://doi.org/10.3390/v10030102
resource representing a document's title	Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam
has PubMed Central identifier	PMC5869495
has PubMed identifier	29495551
schema:publication	Viruses
resource representing a document's body	covid:5669349639eae4f58b4fecca26fcc271094c70ba#body_text
is schema:about of	named entity 'complete' named entity 'rodents' named entity 'transmission' named entity 'rodents' named entity 'remain' named entity 'Vietnamese' covid:arg/5669349639eae4f58b4fecca26fcc271094c70ba named entity 'viruses' named entity 'homologues' named entity 'human' named entity 'zoonoses' named entity 'mammals' named entity 'samples' named entity 'identified' named entity 'serum' named entity 'However' named entity 'potential' named entity 'hepatitis' named entity 'evolution' named entity 'homologues' named entity 'viruses' named entity 'genome sequences' named entity 'zoonoses' named entity 'bat species' named entity 'viruses' named entity 'zoonotic virus' named entity 'viruses' named entity 'mammals' named entity 'rodents' named entity 'RNA' named entity 'bamboo rat' named entity 'Hepatitis Viruses' named entity 'liver' named entity 'Rhizomys' named entity 'Mekong Delta' named entity 'Hipposideros pomona' named entity 'Flaviviridae' named entity 'SSE' named entity 'Hepeviridae' named entity 'PCR' named entity 'liver cells' named entity 'HEV' named entity 'Vietnam' named entity 'Hepeviridae' named entity 'viruses' named entity 'central Africa' named entity 'deep sequencing' named entity 'hepacivirus' named entity 'Qiagen' named entity 'HCV' named entity 'bamboo rat' named entity 'HBV' named entity 'primers' named entity 'HBV' named entity 'Quang Ngai' named entity 'nucleotides' named entity 'hepacivirus' named entity 'viruses' named entity 'Rhizomys pruinosus' named entity 'nuclease' named entity 'Rattus rattus' named entity 'HEV' named entity 'RNA' named entity 'nucleotide' named entity 'HBV' named entity 'mammals' named entity 'HBV' named entity 'Orthohepevirus' named entity 'phylogenetic' named entity 'zoonotic potential' named entity 'zoonotic'

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