About: Clinical characteristics of the lower respiratory tract infection caused by a single infection or coinfection of the human parainfluenza virus in children

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About: Clinical characteristics of the lower respiratory tract infection caused by a single infection or coinfection of the human parainfluenza virus in children Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical characteristics of the lower respiratory tract infection caused by a single infection or coinfection of the human parainfluenza virus in children
Creator	Zhang, Hailin Chen, \| Lv, Fangfang Zhong, Peipei
Source	Medline; PMC
abstract	BACKGROUND: Human parainfluenza virus (HPIV), usually combined with other pathogens, causes lower respiratory tract infection (LRTI) in children. However, clinical characteristics of HPIV coinfection with other pathogens were unclear. This study aimed to investigate the viral and atypical bacterial etiology of LRTI in children and compare the clinical characteristics of HPIV single infection with those of coinfection. METHODS: This study included 1335 patients, aged between 1 to 71 months, diagnosed with LRTI in Yuying Children's Hospital, Zhejiang, China, from December 2013 to June 2015. Nasopharyngeal secretions were collected, and respiratory pathogens were detected using Multiplex polymerase chain reaction. The clinical data of patients were collected and analyzed. RESULTS: At least 1 pathogen was detected in 1181/1335 (88.5%) patients. The pathogens identified most frequently were respiratory syncytial virus, human rhinovirus, HPIV, adenovirus, and human metapneumovirus. The coinfection rate was 24.8%. HPIV coinfection with other viruses was more associated with running nose, shortness of breath, and oxygen support compared with HPIV single infection. Moreover, HPIV coinfection with atypical bacteria was more related to running nose, moist rales, and longer hospital duration compared with HPIV single infection, and also to longer hospital duration compared with coinfection with other viruses. CONCLUSIONS: This study demonstrated that viral infections were highly associated with LRTI and the rate of coinfection was high. HPIV single infection was milder than coinfection with other viruses. Moreover, HPIV coinfection with atypical bacteria was more serious than HPIV single infection and coinfection with other viruses.
has issue date	2019-05-29(xsd:dateTime)
bibo:doi	10.1002/jmv.25499
bibo:pmid	31066075
has license	no-cc
sha1sum (hex)	57692350a6ce9d89e71f11fdf8f2e6586489d4e5
schema:url	https://doi.org/10.1002/jmv.25499
resource representing a document's title	Clinical characteristics of the lower respiratory tract infection caused by a single infection or coinfection of the human parainfluenza virus in children
has PubMed Central identifier	PMC7166436
has PubMed identifier	31066075
schema:publication	J Med Virol
resource representing a document's body	covid:57692350a6ce9d89e71f11fdf8f2e6586489d4e5#body_text
is schema:about of	named entity 'compare' named entity 'collected' named entity 'pathogens' named entity 'infection' named entity 'combined' named entity 'respiratory tract' named entity 'single' named entity 'infection' named entity 'VIRAL AND' named entity 'SECRETIONS' named entity 'HOSPITAL' named entity 'COLLECTED' named entity 'NASOPHARYNGEAL' named entity 'ANALYZED' named entity 'COMBINED' named entity 'PATIENTS' named entity 'USING' named entity 'CAUSES' named entity 'data' named entity 'pathogens' named entity 'patients' named entity 'HPIV' named entity 'infection' named entity 'pneumonia' named entity 'oxygen support' named entity 'LRTI' named entity 'cough' named entity 'respiratory tract' named entity 'atypical bacteria' named entity 'pathogens' named entity 'radiographic' named entity 'bronchiolitis' named entity 'atypical bacteria' named entity 'HPIV' named entity 'detected' named entity 'respiratory' named entity '2013' named entity 'pertussis' named entity 'analysis of variance' named entity 'HPIV' named entity 'cough' named entity 'virus' named entity 'clinical findings' named entity 'infection' named entity 'clinical characteristics' named entity 'coinfection' named entity 'statistically significant' named entity 'atypical' named entity 'clinical' named entity 'viral' named entity 'study' named entity 'Nasopharyngeal secretions' named entity 'China' named entity 'polymerase chain reaction' named entity 'coinfection' named entity 'pathogens' named entity 'lower respiratory tract infection' named entity 'coinfection' named entity 'coinfection' named entity 'SPSS' named entity 'count data' named entity 'pathogens' named entity 'HPIV' named entity 'coinfection' named entity 'coinfection' named entity 'clinical characteristics' named entity 'HPIV' named entity 'HRV' named entity 'coinfection' named entity 'chest X-ray' named entity 'HPIV' named entity 'cough' named entity 'viruses' named entity 'CRP' named entity 'fever' named entity 'viral infections' named entity 'vomiting' named entity 'pertussis'

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