About: Déjà vu: Stimulating open drug discovery for SARS-CoV-2

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Déjà vu: Stimulating open drug discovery for SARS-CoV-2
Creator	Andrade, Carolina Coffee, Megan Ekins, Sean Mottin, Melina Zorn, Kimberley Braga, Rodolpho Foil, Daniel Southan, Christopher Neves, Bruno Puhl, Ana Ramos, Paulo Sousa, Bruna
source	Elsevier; Medline; PMC
abstract	In the past decade we have seen two major Ebola virus outbreaks in Africa, the Zika virus in Brazil and the Americas and the current pandemic of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There is a strong sense of déjà vu because there are still no effective treatments. In the COVID-19 pandemic, despite being a new virus, there are already drugs suggested as active in in vitro assays that are being repurposed in clinical trials. Promising SARS-CoV-2 viral targets and computational approaches are described and discussed. Here, we propose, based on open antiviral drug discovery approaches for previous outbreaks, that there could still be gaps in our approach to drug discovery.
has issue date	2020-04-19(xsd:dateTime)
bibo:doi	10.1016/j.drudis.2020.03.019
bibo:pmid	32320852
has license	no-cc
sha1sum (hex)	57743aceb2d3e286acc75f8e2610602e7061f911
schema:url	https://doi.org/10.1016/j.drudis.2020.03.019
resource representing a document's title	Déjà vu: Stimulating open drug discovery for SARS-CoV-2
has PubMed Central identifier	PMC7167229
has PubMed identifier	32320852
schema:publication	Drug Discov Today
resource representing a document's body	covid:57743aceb2d3e286acc75f8e2610602e7061f911#body_text
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