About: CRISPR in livestock: From editing to printing

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	CRISPR in livestock: From editing to printing
Creator	Crispo, M Dos Santos-Neto, P Menchaca, A Mulet, A
topic	covid:579ba516a18b89a67eedcd6a011528c6a9232a87#this
Source	Elsevier; Medline; PMC
abstract	Abstract Precise genome editing of large animals applied to livestock and biomedicine is nowadays possible since the CRISPR revolution. This review summarizes the latest advances and the main technical issues that determine the success of this technology. The pathway from editing to printing, from engineering the genome to achieving the desired animals, does not always imply an easy, fast and safe journey. When applied in large animals, CRISPR involves time- and cost-consuming projects, and it is mandatory not only to choose the best approach for genome editing, but also for embryo production, zygote microinjection or electroporation, cryopreservation and embryo transfer. The main technical refinements and most frequent questions to improve this disruptive biotechnology in large animals are presented. In addition, we discuss some CRISPR applications to enhance livestock production in the context of a growing global demand of food, in terms of increasing efficiency, reducing the impact of farming on the environment, enhancing pest control, animal welfare and health. The challenge is no longer technical. Controversies and consensus, opportunities and threats, benefits and risks, ethics and science should be reconsidered to enter into the CRISPR era.
has issue date	2020-01-29(xsd:dateTime)
bibo:doi	10.1016/j.theriogenology.2020.01.063
bibo:pmid	32088034
has license	els-covid
sha1sum (hex)	579ba516a18b89a67eedcd6a011528c6a9232a87
schema:url	https://doi.org/10.1016/j.theriogenology.2020.01.063
resource representing a document's title	CRISPR in livestock: From editing to printing
has PubMed Central identifier	PMC7102594
has PubMed identifier	32088034
schema:publication	Theriogenology
resource representing a document's body	covid:579ba516a18b89a67eedcd6a011528c6a9232a87#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/579ba516a18b89a67eedcd6a011528c6a9232a87
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