About: Inferred duration of infectious period of SARS-CoV-2: rapid scoping review and analysis of available evidence for asymptomatic and symptomatic COVID-19 cases

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Inferred duration of infectious period of SARS-CoV-2: rapid scoping review and analysis of available evidence for asymptomatic and symptomatic COVID-19 cases Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Inferred duration of infectious period of SARS-CoV-2: rapid scoping review and analysis of available evidence for asymptomatic and symptomatic COVID-19 cases
Creator	Griffin, John More, Simon Barber, Ann Butler, Francis Byrne, Andrew Casey, Miriam Collins, Áine Hunt, Kevin Lane, Elizabeth Mcaloon, Conor Mcevoy, David O'brien, Kirsty Wall, Patrick Walsh, Kieran
Source	MedRxiv
abstract	Objectives: Our objective was to review the literature on the inferred duration of the infectious period of COVID-19, caused by SARS-COV-2 virus, and provide an overview of the variation depending on the methodological approach. Design: Rapid scoping review. Literature review with fixed search terms, up to 1st April 2020. Central tendency and variation of the parameter estimates for infectious period in (a) asymptomatic (b) symptomatic cases from (i) virological studies (repeated testing), (ii) tracing studies (iii) modelling studies were gathered. Narrative review of viral dynamics. Information sources: Search strategies developed and the following searched: PubMed, Google Scholar, MedRxiv, BioRxiv. Additionally, the Health Information Quality Authority (Ireland) viral load synthesis was utilised, which screened literature from PubMed, Embase, ScienceDirect, NHS evidence, Cochrane, medRxiv and bioRxiv, HRB open databases. Results: There was substantial variation in the estimates, and how infectious period was inferred. One study provided approximate median infectious period for asymptomatic cases of 6.5-9.5 days. Median pre-symptomatic infectious period across studies varied over <1-4 days. Estimated mean time from symptom onset to two negative RT-PCR tests was 13.4 days (95%CI: 10.9-15.8), but was shorter when studies included children or less severe cases. Estimated mean duration from symptom onset to hospital discharge or death (potential maximal infectious period) was 18.1 days (95%CI: 15.1-21.0); time to discharge was on average 4 days shorter than time-to-death. Viral dynamic data and model infectious parameters were often shorter than repeated diagnostic data. Conclusions: There are limitations of inferring infectiousness from repeated diagnosis, viral loads, and viral replication data alone, and also potential patient recall bias relevant to estimating exposure and symptom onset times. Despite this, available data provides a preliminary evidence base to inform models of central tendency for key parameters, and variation for exploring parameter space and sensitivity analysis. Some current models may be underestimating infectious period.
has issue date	2020-04-30(xsd:dateTime)
bibo:doi	10.1101/2020.04.25.20079889
has license	medrxiv
sha1sum (hex)	592458f7eadad2c7a49452e6868c2ab6c3666d3f
schema:url	https://doi.org/10.1101/2020.04.25.20079889
resource representing a document's title	Inferred duration of infectious period of SARS-CoV-2: rapid scoping review and analysis of available evidence for asymptomatic and symptomatic COVID-19 cases
resource representing a document's body	covid:592458f7eadad2c7a49452e6868c2ab6c3666d3f#body_text
is schema:about of	named entity 'literature' named entity 'April' named entity 'literature' named entity 'scoping' named entity 'ScienceDirect' named entity 'Rapid' named entity 'testing' named entity 'repeated' named entity 'studies' named entity 'Literature review' named entity 'period' named entity 'Embase' named entity 'Our' named entity 'virus' named entity 'viral load' named entity 'MedRxiv' named entity 'bioRxiv' named entity 'parameter estimates' named entity 'Health Information' named entity 'asymptomatic' named entity 'virological' named entity 'preprint' named entity 'preprint' named entity 'medRxiv' named entity 'preprint' named entity 'gamma distribution' named entity 'CC-BY 4.0 International license' named entity 'point estimates' named entity 'central tendency' named entity 'RT-PCR' named entity 'sputum' named entity 'preprint' named entity 'medRxiv' named entity 'medRxiv' named entity 'CC-BY 4.0 International license' named entity 'viral load' named entity 'preprint' named entity 'sample sizes' named entity 'preprint' named entity 'viral load' named entity 'preprint' named entity 'viral load' named entity 'peer review' named entity 'April 30' named entity 'symptom' named entity 'preprint' named entity 'infection' named entity 'latent period' named entity 'incubation time' named entity 'preprint' named entity 'viral dynamics' named entity 'medRxiv' named entity 'peer review' named entity 'preprint' named entity '95% CI' named entity 'preprint' named entity 'preprint' named entity 'reverse transcriptase polymerase chain reaction' named entity 'medRxiv' named entity 'parameter estimates' named entity 'Infection' named entity 'CC-BY 4.0 International license' named entity 'preprint' named entity 'China' named entity 'follow-up' named entity 'RT-PCR' named entity 'preprint' named entity 'CC-BY 4.0 International license' named entity '3.5' named entity 'CC-BY 4.0 International license' named entity 'probability function' named entity 'CC-BY 4.0 International license'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software