About: Aspergillus spp. colonization in exhaled breath condensate of lung cancer patients from Puglia Region of Italy

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About: Aspergillus spp. colonization in exhaled breath condensate of lung cancer patients from Puglia Region of Italy Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Aspergillus spp. colonization in exhaled breath condensate of lung cancer patients from Puglia Region of Italy
Creator	Crisetti, Elisabetta Lacedonia, Donato Logrieco, Antonio Logrieco, Giuseppe Susca, Antonia Carpagnano, Giovanna Foschino-Barbaro, Maria Palladino, Grazia
Source	Medline; PMC
abstract	BACKGROUND: Airways of lung cancer patients are often colonized by fungi. Some of these colonizing fungi, under particular conditions, produce cancerogenic mycotoxins. Given the recent interest in the infective origin of lung cancer, with this preliminary study we aim to give our small contribution to this field of research by analysing the fungal microbiome of the exhaled breath condensate of lung cancer patients from Puglia, a region of Italy. METHODS: We enrolled 43 lung cancer patients and 21 healthy subjects that underwent exhaled breath condensate and bronchial brushing collection. The fungal incidence and nature of sample collected were analysed by using a selected media for Aspergillus species. RESULTS: For the first time we were able to analyse the fungal microbioma of the exhaled breath condensate. 27.9% of lung cancer patients showed a presence of Aspergillus niger, or A. ochraceus or Penicillium ssp. while none of the healthy subjects did so. CONCLUSION: The results confirmed the high percentage of fungal colonization of the airways of lung cancer patients from Puglia, suggesting the need to conduct further analyses in this field in order to evaluate the exact pathogenetic role of these fungi in lung cancer as well as to propose efficient, empirical therapy.
has issue date	2014-02-18(xsd:dateTime)
bibo:doi	10.1186/1471-2466-14-22
bibo:pmid	24548615
has license	cc-by
sha1sum (hex)	595019b82939f4fc62cda92fe6eedd34f6933c35
schema:url	https://doi.org/10.1186/1471-2466-14-22
resource representing a document's title	Aspergillus spp. colonization in exhaled breath condensate of lung cancer patients from Puglia Region of Italy
has PubMed Central identifier	PMC3975946
has PubMed identifier	24548615
schema:publication	BMC Pulm Med
resource representing a document's body	covid:595019b82939f4fc62cda92fe6eedd34f6933c35#body_text
is schema:about of	named entity 'aim' named entity 'Airways' named entity 'bronchial' named entity 'lung cancer' named entity 'species' named entity 'analysing' named entity 'incidence' named entity 'patients' named entity 'subjects' named entity 'Methods' named entity 'EXHALED BREATH CONDENSATE' named entity 'OF LUNG CANCER' named entity 'MYCOTOXINS' named entity 'COLLECTED' named entity 'OF LUNG CANCER' named entity 'BRONCHIAL BRUSHING' named entity 'COLONIZATION' named entity 'REGION' named entity 'EVALUATE' named entity 'INTEREST' named entity 'METHODS' named entity 'CONCLUSION' named entity 'FUNGAL COLONIZATION' named entity 'CONFIRMED' named entity 'RESEARCH' named entity 'PRODUCE' named entity 'EXHALED BREATH CONDENSATE' named entity 'PATIENTS' named entity 'NEED' named entity 'ASPERGILLUS NIGER' named entity 'USING' named entity 'RESULTS' named entity 'MEDIA' named entity 'PARTICULAR' named entity 'ASPERGILLUS' named entity 'ITALY' named entity 'NATURE' named entity 'PATIENTS' named entity 'ITALY' named entity 'EMPIRICAL THERAPY' named entity 'PRESENCE OF' named entity 'HEALTHY SUBJECTS' named entity 'SELECTED' named entity 'INCIDENCE' named entity 'COLLECTION' named entity 'RECENT' named entity 'REGION' named entity 'PRELIMINARY STUDY' named entity 'AIM' named entity 'OUR' named entity 'CONDUCT' named entity 'EXACT' named entity 'FUNGAL MICROBIOME' named entity 'AIRWAYS' named entity 'ROLE' named entity 'THESE' named entity 'DID' named entity 'SSP' named entity 'CONDITIONS' named entity 'FUNGI' named entity 'ASPERGILLUS SPECIES' named entity 'FUNGI ' named entity 'EFFICIENT' named entity 'TIME' named entity 'CONTRIBUTION' named entity 'ENROLLED' named entity 'SMALL' named entity 'ORIGIN' named entity 'PENICILLIUM' named entity 'SPP' named entity 'ORDER' named entity 'FIELD' named entity 'GIVEN' named entity 'LUNG CANCER'

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