About: Evidence for widespread infection of African bats with Crimean-Congo hemorrhagic fever-like viruses

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About: Evidence for widespread infection of African bats with Crimean-Congo hemorrhagic fever-like viruses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evidence for widespread infection of African bats with Crimean-Congo hemorrhagic fever-like viruses
Creator	Weber, Friedemann Drosten, Christian Lattwein, Erik Gloza-Rausch, Florian Oppong, Samuel Binger, Tabea Tschapka, Marco Emmerich, Petra Leroy, Eric Vallo, Peter Devignot, Stéphanie Müller, Marcel Cottontail, Veronika Corman, Victor Maganga, Gaël Felix Drexler, Jan
topic	covid:59d3f98d78f2ff993174b173807435e75df8bc3a#this
Source	PMC
abstract	Crimean Congo hemorrhagic fever virus (CCHFV) is a highly virulent tick-borne pathogen that causes hemorrhagic fever in humans. The geographic range of human CCHF cases largely reflects the presence of ticks. However, highly similar CCHFV lineages occur in geographically distant regions. Tick-infested migratory birds have been suggested, but not confirmed, to contribute to the dispersal. Bats have recently been shown to carry nairoviruses distinct from CCHFV. In order to assess the presence of CCHFV in a wide range of bat species over a wide geographic range, we analyzed 1,135 sera from 16 different bat species collected in Congo, Gabon, Ghana, Germany, and Panama. Using a CCHFV glycoprotein-based indirect immunofluorescence test (IIFT), we identified reactive antibodies in 10.0% (114/1,135) of tested bats, pertaining to 12/16 tested species. Depending on the species, 3.6%–42.9% of cave-dwelling bats and 0.6%–7.1% of foliage-living bats were seropositive (two-tailed t-test, p = 0.0447 cave versus foliage). 11/30 IIFT-reactive sera from 10 different African bat species had neutralizing activity in a virus-like particle assay. Neutralization of full CCHFV was confirmed in 5 of 7 sera. Widespread infection of cave-dwelling bats may indicate a role for bats in the life cycle and geographic dispersal of CCHFV.
has issue date	2016-05-24(xsd:dateTime)
bibo:doi	10.1038/srep26637
bibo:pmid	27217069
has license	cc-by
sha1sum (hex)	59d3f98d78f2ff993174b173807435e75df8bc3a
schema:url	https://doi.org/10.1038/srep26637
resource representing a document's title	Evidence for widespread infection of African bats with Crimean-Congo hemorrhagic fever-like viruses
has PubMed Central identifier	PMC4877572
has PubMed identifier	27217069
schema:publication	Sci Rep
resource representing a document's body	covid:59d3f98d78f2ff993174b173807435e75df8bc3a#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/59d3f98d78f2ff993174b173807435e75df8bc3a
is schema:about of	named entity 'EVIDENCE FOR' named entity 'LIKE' named entity 'seropositive' named entity 'species' named entity 'distant' named entity 'However' named entity 'ticks' named entity 'species' covid:arg/59d3f98d78f2ff993174b173807435e75df8bc3a named entity 'T-TEST' named entity 'DWELLING' named entity 'DISPERSAL' named entity 'INDIRECT IMMUNOFLUORESCENCE' named entity 'HEMORRHAGIC FEVER' named entity 'REGIONS' named entity 'GEOGRAPHIC' named entity 'TICK' named entity 'REFLECTS' named entity 'BIRDS' named entity 'PANAMA' named entity 'ANTIBODIES' named entity 'GABON' named entity '2F1' named entity 'OCCUR' named entity 'LIVING' named entity 'WIDESPREAD' named entity 'TAILED' named entity 'USING' named entity 'CONTRIBUTE ' named entity 'ORDER' named entity 'INFECTION' named entity 'LARGELY' named entity 'COLLECTED' named entity 'ACTIVITY' named entity 'CCHFV' named entity 'WIDE' named entity 'MIGRATORY' named entity 'ASSESS' named entity 'ASSAY' named entity 'PRESENCE OF' named entity 'LIFE CYCLE' named entity 'IDENTIFIED' named entity 'CONGO' named entity 'BATS' named entity 'CRIMEAN-CONGO HEMORRHAGIC FEVER' named entity 'VIRUSLIKE PARTICLE' named entity 'RECENTLY' named entity 'TEST' named entity 'DISTANT' named entity 'NOT CONFIRMED' named entity 'CCHF' named entity 'AFRICAN' named entity 'HUMANS' named entity 'CONFIRMED' named entity 'HUMAN' named entity 'BATS' named entity 'WIDESPREAD' named entity 'VIRUSES' named entity 'SIMILAR' named entity 'BUT' named entity 'DISTINCT FROM' named entity 'HAVE' named entity '42.9' named entity 'HIGHLY'

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