About: Detecting SARS‐CoV‐2 RNA in conjunctival secretions: Is it a valuable diagnostic method of COVID‐19?

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About: Detecting SARS‐CoV‐2 RNA in conjunctival secretions: Is it a valuable diagnostic method of COVID‐19? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Detecting SARS‐CoV‐2 RNA in conjunctival secretions: Is it a valuable diagnostic method of COVID‐19?
Creator	Arriola-Villalobos, Pedro Burgos-Blasco, Barbara Güemes-Villahoz, Noemi Arribi-Vilela, Ana Cuiña-Sardiña, Ricardo Delgado-Iribarren, Alberto Julián García-Feijoó, \| Rico-Luna, Carla
source	Medline; PMC
abstract	The main purpose of this study is to evaluate the presence of viral RNA of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) in conjunctival swab specimen of coronavirus disease 2019 (COVID‐19) patients with and without conjunctivitis to establish the diagnostic value of reverse transcription‐polymerase chain reaction (RT‐PCR) in each case and to describe its clinical characteristics. A cross‐sectional study was conducted at the Hospital Clinico San Carlos of Madrid, Spain. Thirty‐six subjects from the COVID admission unit with laboratory‐confirmed SARS‐CoV‐2 infection were included. Conjunctival swabs were collected from 18 patients with conjunctivitis and 18 patients without conjunctivitis and RT‐PCR was performed. Conjunctival swab was collected from both eyes of 36 patients (72 eyes), detecting SARS‐CoV‐2 RNA in conjunctival swab of two patients (5.5%). Among the 18 patients with conjunctivitis, only one of them (5.5%) showed positive results. Likewise, SARS‐CoV‐2 RNA was detected in one patient without conjunctivitis (5.5%). The mean age of the 36 patients was 67.9 years (range, 28‐92 years) and the male‐to‐female ratio was 0.44 (16:20). The mean days since the onset of COVID‐19 symptoms until conjunctivitis manifestation was 8 (range, 1‐24 days). The mean duration of the conjunctivitis was 3 days (range, 1‐7 days). SARS‐CoV‐2 RNA may be detected in conjunctival swabs of both patients with and without conjunctivitis. This study revealed the same rate of positive results amongst the group with and without conjunctivitis, suggesting that detecting SARS‐CoV‐2 in ocular fluids is not conditioned on the presence of conjunctivitis. The presence of SARS‐CoV‐2 RNA in ocular samples highlights the role of the eye as a possible route of transmission of the disease.
has issue date	2020-07-06(xsd:dateTime)
bibo:doi	10.1002/jmv.26219
bibo:pmid	32579256
has license	no-cc
sha1sum (hex)	5a335444e8cf2bb365519d60ce2b9b4c0da7f514
schema:url	https://doi.org/10.1002/jmv.26219
resource representing a document's title	Detecting SARS‐CoV‐2 RNA in conjunctival secretions: Is it a valuable diagnostic method of COVID‐19?
has PubMed Central identifier	PMC7361904
has PubMed identifier	32579256
schema:publication	J Med Virol
resource representing a document's body	covid:5a335444e8cf2bb365519d60ce2b9b4c0da7f514#body_text
is schema:about of	named entity 'conjunctivitis' named entity 'group' named entity 'symptoms' named entity 'RNA' named entity 'COVID-19' named entity 'positive' named entity 'eye' named entity 'reverse' named entity 'cross-sectional study' named entity 'ratio' named entity 'RNA' named entity 'coronavirus disease 2019' named entity 'conjunctivitis' named entity 'ocular' named entity 'Spain' named entity 'detecting' named entity 'range' named entity 'eyes' named entity 'patients' named entity 'SARS-CoV-2' named entity 'swab' named entity 'coronavirus disease 2019' named entity 'conjunctivitis' named entity 'infection' named entity 'RT-PCR' named entity 'RNA' named entity 'conjunctival' named entity 'conjunctivitis' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'conjunctivitis' named entity 'SARS-CoV-2' named entity 'CURB-65' named entity 'transport medium' named entity 'chest X-ray' named entity 'pneumonia' named entity 'Europe' named entity 'COVID-19' named entity 'nasopharyngeal swab' named entity 'C-reactive protein' named entity 'conjunctivitis' named entity 'COVID-19' named entity 'conjunctival' named entity 'conjunctivitis' named entity 'conjunctivitis' named entity 'SARS-CoV-2' named entity 'RT-PCR' named entity 'conjunctival' named entity 'etiologies' named entity 'RT-PCR' named entity 'SARS-CoV-2' named entity 'conjunctivitis' named entity 'clinical characteristics' named entity 'Italy' named entity 'conjunctivitis' named entity 'Copan' named entity 'pseudomembranes' named entity 'conjunctival' named entity 'dyspnea' named entity 'laboratory test' named entity 'physical examination' named entity 'viral dynamics' named entity 'SARS-CoV-2' named entity 'conjunctivitis' named entity 'viral load' named entity 'conjunctivitis' named entity 'conjunctivitis' named entity 'SARS-CoV-2' named entity 'conjunctivitis' named entity 'RT-PCR' named entity 'SARS-CoV-2' named entity 'RNA' named entity 'conjunctivitis'

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