About: Deaths in SARS-Cov-2 Positive Patients in Italy: The Influence of Underlying Health Conditions on Lethality

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About: Deaths in SARS-Cov-2 Positive Patients in Italy: The Influence of Underlying Health Conditions on Lethality Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Deaths in SARS-Cov-2 Positive Patients in Italy: The Influence of Underlying Health Conditions on Lethality
Creator	Azara, Antonio Dettori, Marco Castiglia, Paolo Deiana, Giovanna Delogu, Fiorenzo Gessa, Isabella Steri, Giorgio Stroscio, Filippo Tidore, Marcello Vargiu, Gavino
source	Medline; PMC
abstract	This study aims to underline the clinical characteristics of patients who died after testing positive for SARS-CoV-2 infection in one region of Italian and to evaluate the influence of underlying health conditions on the fatal outcome. A matched case-control study was designed by analyzing the data regarding positive subjects observed up to April 21, 2020. The case fatality rate was 7.9%, with a higher proportion of deaths in men than women. The specific standardized mortality ratio was 0.15—0.13 for males and 0.2 for females, showing that mortality is much lower than expected. Cardiovascular diseases, chronic lung diseases and diabetes mellitus showed a significant association with the outcome. Although the case fatality rate in Sardinia in regard to age and gender patterns seems to be similar to that for Italy as a whole, its quantitative value was far lower than the national one and possible explanations might include the genetic characteristics of the Sardinian population or the immediate closure of its borders as soon as the epidemic started. Our results highlighted that lethality is strongly dependent on the presence of multiple concomitant serious diseases. It is important to have epidemiological strategies for effective guidance on public health actions in order to improve chances of survival.
has issue date	2020-06-21(xsd:dateTime)
bibo:doi	10.3390/ijerph17124450
bibo:pmid	32575825
has license	cc-by
sha1sum (hex)	5befbf38862f5372fbf58bee407b78f440fcffa3
schema:url	https://doi.org/10.3390/ijerph17124450
resource representing a document's title	Deaths in SARS-Cov-2 Positive Patients in Italy: The Influence of Underlying Health Conditions on Lethality
has PubMed Central identifier	PMC7344703
has PubMed identifier	32575825
schema:publication	Int J Environ Res Public Health
resource representing a document's body	covid:5befbf38862f5372fbf58bee407b78f440fcffa3#body_text
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