About: Delivery technologies for human vaccines

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Delivery technologies for human vaccines
Creator	Almond, Jeffrey De Taisne, Charles Moingeon, Philippe
source	Medline; PMC
abstract	There is currently intense research activity aimed at the development of new delivery systems for vaccines. The goal is to identify optimal methods for presenting target antigens to the immune system in a manner that will elicit immune responses appropriate for protection against, or treatment of, a specific disease. Several different approaches to this general goal have been developed, some are empirical and remain poorly understood, others are more rational, being based, for example, on mimicking natural infections in vivo or on targeting particular features of the immune system. This article will review three categories of delivery systems: (i) adjuvants and formulations; (ii) antigen vectors, including live attenuated micro-organisms and synthetic vectors; and (iii) novel devices for vaccine administration. The review will be restricted to late stage developments in the field of human vaccination.
has issue date	2002-07-01(xsd:dateTime)
bibo:doi	10.1093/bmb/62.1.29
bibo:pmid	12176848
has license	no-cc
sha1sum (hex)	5c03f7971e51a825be6a88d675b1cd05d1c3b527
schema:url	https://doi.org/10.1093/bmb/62.1.29
resource representing a document's title	Delivery technologies for human vaccines
has PubMed Central identifier	PMC7110014
has PubMed identifier	12176848
schema:publication	Br Med Bull
resource representing a document's body	covid:5c03f7971e51a825be6a88d675b1cd05d1c3b527#body_text
is schema:about of	named entity 'presenting' named entity 'natural' named entity 'vaccines' named entity 'TECHNOLOGIES' named entity 'NEW' named entity 'UNDERSTOOD' named entity 'APPROACHES' named entity 'TARGETING' named entity 'METHODS' named entity 'DISEASE' named entity 'IMMUNE SYSTEM' named entity 'ELICIT' named entity 'RESEARCH ACTIVITY' named entity 'IN THE FIELD' named entity 'TREATMENT' named entity 'PRESENTING' named entity 'OPTIMAL' named entity 'INFECTIONS' named entity 'VECTORS' named entity 'NOVEL' named entity 'LATE STAGE' named entity 'MICRO-ORGANISMS' named entity 'GENERAL' named entity 'BEING' named entity 'NATURAL' named entity 'APPROPRIATE' named entity 'TO IDENTIFY' named entity 'VACCINES' named entity 'VACCINE ADMINISTRATION' named entity 'BASED' named entity 'HUMAN' named entity 'DELIVERY' named entity 'DEVELOPMENT' named entity 'SPECIFIC' named entity 'IMMUNE RESPONSES' named entity 'ADJUVANTS' named entity 'CATEGORIES' named entity 'DEVICES' named entity 'POORLY' named entity 'HAVE' named entity 'HUMAN VACCINATION' named entity 'RESTRICTED' named entity 'INCLUDING' named entity 'EXAMPLE' named entity 'PARTICULAR' named entity 'ANTIGENS' named entity 'PROTECTION' named entity 'ATTENUATED' named entity 'LIVE' named entity 'REVIEW' named entity 'TARGET' named entity 'IN VIVO' named entity 'DIFFERENT' named entity '28I' named entity 'INTENSE' named entity 'CURRENTLY' named entity 'EMPIRICAL' named entity 'SYNTHETIC' named entity 'FEATURES' named entity 'DELIVERY SYSTEMS' named entity 'VACCINES' named entity 'GOAL' named entity 'ANTIGEN' named entity 'ARTICLE' named entity 'target' named entity 'vaccination' named entity 'antigen' named entity 'identify' named entity 'rational' named entity 'poorly understood' named entity 'vectors' named entity 'intense' named entity 'The goal' named entity 'antigen presenting cells' named entity 'high temperature' named entity 'poxviruses' named entity 'nebulizer' named entity 'pro-inflammatory' named entity 'prime-boost'

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