About: Pathophysiology of acute fibrinous and organizing pneumonia

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Pathophysiology of acute fibrinous and organizing pneumonia – Clinical and morphological spectra Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Pathophysiology of acute fibrinous and organizing pneumonia – Clinical and morphological spectra
Creator	Carvalho, Lina Casanova, Paula Pimentel, Jorge Santos, Cláudia Serra, Paula Sousa, Eduardo Oliveira, Rui Pedro Baptista, João
Source	Elsevier; Medline; PMC
abstract	Abstract Acute Fibrinous and Organizing Pneumonitis (AFOP) is a disease with histopathological pattern characterized by the presence of intra-alveolar fibrin in the form of fibrin “balls” and organizing pneumonia represented by inflammatory myofibroblastic polyps. Symptoms of this rare interstitial pulmonary disease can be either acute or sub-acute and it can rapidly progress to death. Diagnosis should be considered in the Intensive Care Unit (ICU) if patients’ symptomatology and radiology correlates with non-responding or progressive pneumonia and when morphology, on biopsies, encompasses criteria of diffuse alveolar damage (DAD) and organizing pneumonia (OP) balancing in between. Three clinical cases of patients presenting severe lung disease requiring mechanical ventilation and prolonged intensive care fitted on the variable spectra of AFOP histopathology and had poor outcome: a 23 year-old women had AFOP in the context of antiphospholipid syndrome pulmonary compromise; a 35 year-old man developed a letal intensive care pneumonia with AFOP pattern registered in post-mortem biopsy; and a 79 year-old man died 21 days after intensive care unit treatment of a sub-pleural organizing pneumonia with intra-alveolar fibrin, seen in post-mortem biopsy. The predominance of acute fibrin alveolar deposition pattern is helpful in raising AFOP differential diagnosis while organizing pneumonia pattern establishes a wider range of diagnosis that can go till solitary pulmonary nodule, remaining indefinite to suggest diagnosis. The performance time of biopsy in a larger number of clinical cases may be helpful in establishing the evolutionary morphological pattern, taking in mind the poor outcome of the disease, deserving rapid diagnosis to define treatment.
has issue date	2019-12-31(xsd:dateTime)
bibo:doi	10.1016/j.pathophys.2019.04.001
bibo:pmid	31076239
has license	els-covid
sha1sum (hex)	5d57be6861370c09c063237a35b5688072631ca2
schema:url	https://doi.org/10.1016/j.pathophys.2019.04.001
resource representing a document's title	Pathophysiology of acute fibrinous and organizing pneumonia – Clinical and morphological spectra
has PubMed Central identifier	PMC7126839
has PubMed identifier	31076239
schema:publication	Pathophysiology
resource representing a document's body	covid:5d57be6861370c09c063237a35b5688072631ca2#body_text
is schema:about of	named entity 'rapidly' named entity 'rare' named entity 'Diagnosis' named entity 'correlates' named entity 'Intensive Care Unit (ICU)' named entity 'organizing pneumonia' named entity 'PRESENCE OF' named entity 'DEATH' named entity 'NON-' named entity 'PROGRESS' named entity 'SYMPTOMATOLOGY' named entity 'ORGANIZING' named entity 'IS A' named entity 'CRITERIA' named entity 'CHARACTERIZED' named entity 'FIBRINOUS' named entity 'BIOPSIES' named entity 'ALVEOLAR' named entity 'RADIOLOGY' named entity 'PNEUMONIA' named entity 'ORGANIZING PNEUMONIA' named entity 'PROGRESSIVE' named entity 'SYMPTOMS' named entity 'ACUTE' named entity 'ORGANIZING PNEUMONIA' named entity 'PATTERN' named entity 'IN BETWEEN' named entity 'ACUTE' named entity 'INFLAMMATORY' named entity 'RARE' named entity 'POLYPS' named entity 'PATIENTS' named entity 'DISEASE' named entity 'FIBRIN' named entity 'MORPHOLOGY' named entity 'INTENSIVE CARE UNIT' named entity 'CLINICAL' named entity 'SPECTRA' named entity 'INTERSTITIAL PULMONARY DISEASE' named entity 'MORPHOLOGICAL' named entity 'PATHOPHYSIOLOGY' named entity 'DIFFUSE ALVEOLAR DAMAGE' named entity 'BALANCING' named entity 'PNEUMONITIS' named entity 'INTRA' named entity 'HISTOPATHOLOGICAL' named entity 'FIBRINOUS' named entity 'EITHER' named entity 'CONSIDERED' named entity 'SUB-' named entity 'RAPIDLY' named entity 'FORM' named entity 'DIAGNOSIS' covid:arg/5d57be6861370c09c063237a35b5688072631ca2 named entity 'pattern' named entity 'histopathological' named entity 'biopsies' named entity 'histopathological' named entity 'organizing pneumonia' named entity 'diffuse alveolar damage' named entity 'morphological' named entity 'clinical presentation' named entity 'pneumonia' named entity 'immunosuppressive agents' named entity 'ankylosing spondylitis' named entity 'emergency room' named entity 'fibrin' named entity 'hyaline' named entity 'biopsies' named entity 'pneumonia' named entity 'sputum' named entity 'interstitial pneumonitis' named entity 'bronchioles' named entity 'macrophages'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software