About: SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage

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About: SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage
Creator	Rawlinson, William Clifford, Vanessa Bansal, Nidhi Klein C#, Laura Stella, Alberto Stelzer-Braid, Sacha Turville, Stuart Walker, Gregory
Source	MedRxiv
abstract	As the COVID-19 pandemic evolves, human milk banks worldwide continue to provide donor human milk to vulnerable infants who lack access to mothers own milk. Under these circumstances, ensuring the safety of donor human milk is paramount, as the risk of vertical transmission of SARS-CoV-2 is not well understood. Here, we investigate the inactivation of SARS-CoV-2 in human milk by pasteurisation, and the stability of SARS-CoV-2 in human milk under cold storage (freezing or refrigeration). Following heating to 63{degrees}C or 56{degrees}C for 30 minutes, SARS-CoV-2 replication competent (i.e. live) virus was undetected in both human milk and the control medium. Cold storage of SARS-CoV-2 in human milk (either at 4{degrees}C or -30{degrees}C) did not significantly impact infectious viral load over a 48 hour period. Our findings demonstrate that SARS-CoV-2 can be effectively inactivated by Holder pasteurisation, and confirm that existing milk bank processes will effectively mitigate the risk of transmission of SARS-COV-2 to vulnerable infants through pasteurised donor human milk.
has issue date	2020-06-20(xsd:dateTime)
bibo:doi	10.1101/2020.06.18.20134395
has license	medrxiv
sha1sum (hex)	600114ea9a5f967601999f7fe7605c6b9999b222
schema:url	https://doi.org/10.1101/2020.06.18.20134395
resource representing a document's title	SARS-CoV-2 in human milk is inactivated by Holder pasteurization but not cold storage
resource representing a document's body	covid:600114ea9a5f967601999f7fe7605c6b9999b222#body_text
is schema:about of	named entity 'effectively' named entity 'SARS-CoV-2' named entity 'mitigate' named entity 'pasteurisation' named entity 'donor' named entity 'human milk' named entity 'TO PROVIDE' named entity 'DID' named entity 'UNDERSTOOD' named entity 'THESE' named entity 'SAFETY' named entity 'INACTIVATION' named entity 'CONTINUE' named entity 'FOLLOWING' covid:arg/600114ea9a5f967601999f7fe7605c6b9999b222 named entity 'replication' named entity 'Under' named entity 'Here' named entity 'SARS-CoV-2' named entity 'live' named entity 'effectively' named entity 'pasteurised' named entity 'donor' named entity 'access' named entity 'SARS-CoV-2' named entity 'human milk' named entity 'evolves' named entity 'banks' named entity 'human milk' named entity 'risk' named entity 'Following' named entity 'virus' named entity 'vulnerable' named entity 'cold storage' named entity 'risk of transmission' named entity 'pasteurisation' named entity 'vertical transmission' named entity 'virus' named entity 'refrigeration' named entity 'SARS-CoV-2' named entity 'milk banks' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'pasteurised' named entity 'human milk' named entity 'pasteurisation' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'medRxiv' named entity 'human milk' named entity 'cold storage' named entity 'preprint' named entity 'inoculation' named entity 'milk bank' named entity 'breast milk' named entity 'human milk' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'pasteurisation' named entity 'pasteurisation' named entity 'nucleic acid' named entity 'COVID-19 pandemic' named entity 'doi' named entity 'enveloped viruses' named entity 'preprint' named entity 'human milk' named entity 'preprint' named entity 'medRxiv' named entity 'microbial' named entity 'serological' named entity 'vertical transmission' named entity 'pasteurisation' named entity 'virus' named entity 'risk of transmission' named entity 'Australian Red Cross Lifeblood' named entity 'virus' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2'

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