About: Colorimetric detection of controlled assembly and disassembly of aptamers on unmodified gold nanoparticles

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About: Colorimetric detection of controlled assembly and disassembly of aptamers on unmodified gold nanoparticles Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Colorimetric detection of controlled assembly and disassembly of aptamers on unmodified gold nanoparticles
Creator	Awazu, Koichi Lakshmipriya, Thangavel Gopinath, Subash
Source	Elsevier; Medline; PMC
abstract	Abstract Aptamers are nucleic acid ligands that are generated artificially by in vitro selection and behave similar to antibodies. The development of aptamer-based sensing systems or strategies has been in vogue for the past few decades, because aptamers are smaller in size, stable, cheaper and undergo easier modifications. Owing to these advantages, several facile aptamer-based colorimetric strategies have been created by controlling the assembly and disassembly of aptamers on unmodified gold nanoparticle probes. As these kinds of assay systems are rapid and can be visualized unaided by instruments, they have recently become an attractive method of choice. The formation of purple-colored aggregates (attraction) from the red dispersed (repulsion) state of GNPs in the presence of mono- or divalent ions is the key principle behind this assay. Due to its simplicity and versatility, this assay can be an alternative to existing diagnostic assays. Here, we have investigated the critical elements involved in colorimetric assays, and have screened different proteins and small ligands to evaluate biofouling on GNPs.
has issue date	2014-01-15(xsd:dateTime)
bibo:doi	10.1016/j.bios.2013.07.037
bibo:pmid	23948242
has license	els-covid
sha1sum (hex)	603a2415d7b9818f7becaf745a9fc8dc58869f79
schema:url	https://doi.org/10.1016/j.bios.2013.07.037
resource representing a document's title	Colorimetric detection of controlled assembly and disassembly of aptamers on unmodified gold nanoparticles
has PubMed Central identifier	PMC7125824
has PubMed identifier	23948242
schema:publication	Biosensors and Bioelectronics
resource representing a document's body	covid:603a2415d7b9818f7becaf745a9fc8dc58869f79#body_text
is schema:about of	named entity 'DISASSEMBLY' named entity 'assay' named entity 'involved' named entity 'ASSEMBLY' named entity 'CHOICE' named entity 'RED' named entity 'PAST' named entity 'SIZE' named entity 'STRATEGIES' named entity 'ELEMENTS' named entity 'PRESENCE OF' named entity 'PROTEINS' named entity 'SMALL' named entity 'RECENTLY' named entity 'CREATED BY' named entity 'LIGANDS' named entity 'DUE TO' named entity 'EVALUATE' named entity 'DISASSEMBLY' named entity 'AGGREGATES' named entity 'SYSTEMS' named entity 'RAPID' named entity 'DEVELOPMENT' named entity 'CONTROLLED' named entity 'APTAMERS' named entity 'COLORIMETRIC DETECTION' named entity 'GOLD' named entity 'NANOPARTICLES' named entity 'GOLD NANOPARTICLE' named entity 'INVOLVED' named entity 'COLORIMETRIC ASSAYS' named entity 'INSTRUMENTS' named entity 'ITS' named entity 'INVESTIGATED' named entity 'ATTRACTIVE' named entity 'PRINCIPLE' named entity 'IONS' named entity 'SIMILAR' named entity 'KEY' named entity 'THESE' named entity 'COLORED' named entity 'CRITICAL' named entity 'ASSEMBLY' named entity 'ALTERNATIVE' named entity 'DIFFERENT' named entity 'ASSAY' named entity 'CONTROLLING' named entity 'BASED' named entity 'VISUALIZED' named entity 'HERE' named entity 'IN VITRO SELECTION' named entity 'NUCLEIC ACID' named entity 'FORMATION' named entity 'STABLE' named entity 'STATE' named entity 'MONO' named entity 'METHOD' named entity 'BIOFOULING' named entity 'PROBES' named entity 'APTAMER' named entity 'SENSING SYSTEMS' named entity 'DISPERSED' named entity 'ANTIBODIES' named entity 'GENERATED' named entity 'APTAMERS' named entity 'PURPLE' named entity 'VOGUE' named entity 'HAVE' named entity 'KINDS' named entity 'DIAGNOSTIC' named entity 'SMALLER' named entity 'UNAIDED' covid:arg/603a2415d7b9818f7becaf745a9fc8dc58869f79 named entity 'created' named entity 'attractive' named entity 'systems' named entity 'assays' named entity 'elements' named entity 'generated'

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