About: Discovery of a novel canine respiratory coronavirus support genetic recombination among betacoronavirus1

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Discovery of a novel canine respiratory coronavirus support genetic recombination among betacoronavirus1 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Discovery of a novel canine respiratory coronavirus support genetic recombination among betacoronavirus1
Creator	Zhao, Jincun Tan, Wenjie Wang, Yanqun Lou, Yongliang Chen, Yingzhu Qin, Kun Wu, Bingjie Lu, Shuai
Source	Elsevier; Medline; PMC
abstract	Abstract Although canine respiratory coronavirus (CRCoV) is an important respiratory pathogen that is prevalent in many countries, only one complete genome sequence of CRCoV (South Korea strain K37) has been obtained to date. Genome-wide analyses and recombination have rarely been conducted, as small numbers of samples and limited genomic characterization have previously prevented further analyses. Herein, we report a unique CRCoV strain, denoted strain BJ232, derived from a CRCoV-positive dog with a mild respiratory infection. Phylogenetic analysis based on complete genome of all available coronaviruses consistently show that CRCoV BJ232 is most closely related to human coronavirus OC43 (HCoV-OC43) and BCoV, forming a separate clade that split off early from other Betacoronavirus 1. Based on the phylogenetic and SimPlot analysis we propose that CRCoV-K37 was derived from genetic recombination between CRCoV-BJ232 and BCoV. In detail, spike (S) gene of CRCoV-K37 clustered with CRCoV-BJ232. However orf1ab, membrane (M) and nucleocapsid (N) genes were more related to Bovine coronavirus (BCoV) than CRCoV-B232. Molecular epidemic analysis confirmed the prevalence of CRCoV-BJ232 lineage around the world for a long time. Recombinant events among Betacoronavirus 1 may have implications for CRCoV transmissibility. All these findings provide further information regarding the origin of CRCoV.
has issue date	2017-06-02(xsd:dateTime)
bibo:doi	10.1016/j.virusres.2017.05.006
bibo:pmid	28506792
has license	els-covid
sha1sum (hex)	613190af3c40eb22e479079068b6d7aed237faad
schema:url	https://doi.org/10.1016/j.virusres.2017.05.006
resource representing a document's title	Discovery of a novel canine respiratory coronavirus support genetic recombination among betacoronavirus1
has PubMed Central identifier	PMC7114567
has PubMed identifier	28506792
schema:publication	Virus Research
resource representing a document's body	covid:613190af3c40eb22e479079068b6d7aed237faad#body_text
is schema:about of	named entity 'DISCOVERY' named entity 'RECOMBINANT' named entity 'MAY HAVE' named entity 'GENOMIC' named entity 'REPORT' named entity 'ANALYSIS' named entity 'IMPORTANT' named entity 'CONFIRMED' named entity 'OBTAINED' named entity 'CANINE RESPIRATORY CORONAVIRUS' named entity 'NUCLEOCAPSID' named entity 'clade' named entity 'mild' named entity 'complete' named entity 'genes' named entity 'coronavirus' named entity 'genome' named entity 'detail' named entity 'confirmed' named entity 'genetic recombination' named entity 'PREVIOUSLY' named entity 'FINDINGS' named entity 'INFORMATION' named entity 'AVAILABLE' named entity 'NOVEL' named entity 'CANINE RESPIRATORY CORONAVIRUS' named entity 'DOG' named entity 'RECOMBINATION' named entity 'UNIQUE' named entity 'EPIDEMIC' named entity 'HAVE' named entity 'POSITIVE' named entity 'PREVALENT' named entity 'COMPLETE' named entity 'RELATED' named entity 'ORF1AB' named entity 'WIDE' named entity 'TIME' named entity 'PHYLOGENETIC ANALYSIS' named entity '28S' named entity 'SEPARATE' named entity 'EVENTS' named entity 'ORIGIN' named entity 'GENETIC RECOMBINATION' named entity 'CLUSTERED' named entity 'PREVALENCE' named entity 'THESE' named entity 'CORONAVIRUSES' named entity 'K37' named entity 'DERIVED' named entity 'SAMPLES' named entity 'BASED' named entity 'MEMBRANE' named entity 'SPIKE' named entity 'PATHOGEN' named entity 'BETACORONAVIRUS 1' named entity 'RARELY' named entity 'EARLY' named entity 'LINEAGE' named entity 'GENOME' named entity 'RESPIRATORY INFECTION' named entity 'STRAIN' named entity 'LIMITED' named entity 'GENETIC RECOMBINATION' named entity 'SUPPORT' named entity 'MOLECULAR' named entity 'CLADE' named entity 'GENE' named entity 'GENES' named entity 'OC43' named entity 'BOVINE CORONAVIRUS' named entity 'GENOME SEQUENCE' named entity 'NUMBERS' named entity 'MILD'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software