About: Acute lower respiratory infections on lung sequelae in Cambodia, a neglected disease in highly tuberculosis-endemic country

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About: Acute lower respiratory infections on lung sequelae in Cambodia, a neglected disease in highly tuberculosis-endemic country Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Acute lower respiratory infections on lung sequelae in Cambodia, a neglected disease in highly tuberculosis-endemic country
Creator	Buchy, Philippe Rith, Sareth Tarantola, Arnaud Vong, Sirenda Guillard, Bertrand Borand, Laurence Cheng, Sokleaph Goyet, Sophie Hem, Sopheak Mayaud, Charles Rammaert, Blandine Te, Vantha Lorn Try, Patrich
Source	Elsevier; Medline; PMC
abstract	Summary Background Little is known about post-infectious pulmonary sequelae in countries like Cambodia where tuberculosis is hyper-endemic and childhood pulmonary infections are highly frequent. We describe the characteristics of hospitalized Cambodian patients presenting with community-acquired acute lower respiratory infections (ALRI) on post-infectious pulmonary sequelae (ALRIPS). Methods Between 2007 and 2010, inpatients ≥15 years with ALRI were prospectively recruited. Clinical, biological, radiological and microbiological data were collected. Chest radiographs were re-interpreted by experts to compare patients with ALRIPS, on previously healthy lungs (ALRIHL) and active pulmonary tuberculosis (TB). Patients without chest radiograph abnormality or with abnormality suggestive as other chronic respiratory diseases were excluded from this analysis. Results Among the 2351 inpatients with community-acquired ALRI, 1800 were eligible: 426 (18%) ALRIPS, 878 (37%) ALRIHL and 496 (21%) TB. ALRIPS patients had less frequent fever than other ALRI (p < 0.001) and more productive cough than ALRIHL (p < 0.001). Streptococcus pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa accounted for 83% of ALRIPS group positive cultures. H. influenzae and P. aeruginosa were significantly associated with ALRIPS compared with ALRIHL. Treatment was appropriate in 58% of ALRIPS patients. Finally, 79% of ALRIPS were not recognized by local clinicians. In-hospital mortality was low (1%) but probably underestimated in the ALRIPS group. Conclusion ALRIPS remains often misdiagnosed as TB with inappropriate treatment in low-income countries. Better-targeted training programs would help reduce the morbidity burden and financial costs.
has issue date	2013-10-31(xsd:dateTime)
bibo:doi	10.1016/j.rmed.2013.07.018
bibo:pmid	23937802
has license	els-covid
sha1sum (hex)	61d5fb57988a7422b076d82490bf71974d7cf15b
schema:url	https://doi.org/10.1016/j.rmed.2013.07.018
resource representing a document's title	Acute lower respiratory infections on lung sequelae in Cambodia, a neglected disease in highly tuberculosis-endemic country
has PubMed Central identifier	PMC7125659
has PubMed identifier	23937802
schema:publication	Respiratory Medicine
resource representing a document's body	covid:61d5fb57988a7422b076d82490bf71974d7cf15b#body_text
is schema:about of	named entity 'TUBERCULOSIS' named entity 'Streptococcus' named entity 'lungs' named entity 'local' named entity 'respiratory infections' named entity 'clinicians' named entity 'P. aeruginosa' named entity 'Patients' named entity 'pulmonary' named entity 'neglected disease' named entity 'REMAINS' named entity 'CAMBODIA' named entity 'PULMONARY INFECTIONS' named entity 'PRESENTING' named entity 'RESULTS' named entity 'BACKGROUND' named entity 'LIKE' named entity 'PREVIOUSLY' named entity 'BUT' named entity 'COSTS' named entity 'FREQUENT' named entity 'ABNORMALITY' named entity 'METHODS' named entity 'CAMBODIA' named entity 'YEARS' named entity 'HAEMOPHILUS INFLUENZAE' named entity '2351' named entity 'HYPER' named entity 'ANALYSIS' named entity 'SUGGESTIVE' named entity 'HEALTHY' named entity 'TRAINING PROGRAMS' named entity 'PNEUMONIAE' named entity 'INTERPRETED' named entity '0.001' named entity 'PSEUDOMONAS AERUGINOSA' named entity 'INFECTIOUS' named entity 'PRODUCTIVE COUGH' named entity 'LOCAL' named entity 'PROBABLY' named entity 'DISEASE' named entity 'LUNG' named entity 'NEGLECTED' named entity 'SEQUELAE' named entity 'COUNTRY' named entity 'RESPIRATORY INFECTIONS' named entity 'ACUTE' named entity 'HIGHLY' named entity 'LOWER' named entity 'ENDEMIC' named entity 'LITTLE' named entity 'ELIGIBLE' named entity 'TARGETED' named entity 'COMPARED' named entity 'APPROPRIATE' named entity 'CAMBODIAN' named entity 'ABOUT' named entity 'HIGHLY' named entity 'DESCRIBE' named entity 'COUNTRIES' named entity 'TREATMENT' named entity 'ACQUIRED' named entity 'GROUP' named entity 'PATIENTS' named entity 'RIPS' named entity 'CHEST RADIOGRAPH' named entity 'RESPIRATORY MEDICINE' named entity 'CONCLUSION' named entity 'REDUCE'

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