About: Applications of genetic engineering in veterinary medicine

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Applications of genetic engineering in veterinary medicine
Creator	Ciftci, Kadriye Trovitch, Peter
Source	Elsevier; Medline; PMC
abstract	Abstract A mutation of just one gene will cause abnormal cell behavior leading to the synthesis of a dysfunctional protein. This mutation will inevitably result in the cell functioning only marginally or not at all. Other genetic mutations interfere with the cell’s normal life cycle, especially the cell-division cycle. The goal behind recombinant DNA technology is to deliver the correct version of a mutated gene to the cell so that the expression will lead to the normal production of protein and the restoration of normal cell function. This can be considered qualitatively different from other conventional treatments due to genetic material being a putative therapeutic agent. By altering the genetic material of cells, gene therapy may correct, or one day cure, the specific disease pathophysiology. Genetic engineering has been used in veterinary medicine to diagnose, prevent and treat diseases, breed different species and produce transgenic animals for therapeutic proteins or xenografting. In this review the current status of recombinant DNA technology and its application in veterinary medicine together with the obstacles to, and applications of, genetic engineering in veterinary medicine are discussed.
has issue date	2000-09-15(xsd:dateTime)
bibo:doi	10.1016/s0169-409x(00)00077-6
bibo:pmid	10967221
has license	els-covid
sha1sum (hex)	622f303bb2041b5c20fe2dd55914d8fd4bfb776c
schema:url	https://doi.org/10.1016/s0169-409x%2800%2900077-6
resource representing a document's title	Applications of genetic engineering in veterinary medicine
has PubMed Central identifier	PMC7130230
has PubMed identifier	10967221
schema:publication	Advanced Drug Delivery Reviews
resource representing a document's body	covid:622f303bb2041b5c20fe2dd55914d8fd4bfb776c#body_text
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