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About:
An Update on Current Therapeutic Drugs Treating COVID-19
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
An Update on Current Therapeutic Drugs Treating COVID-19
Creator
Liu, Xia
Liu, Zhigang
Amorosa, Louis
Brunetti, Luigi
Chou, Jordan
Hudlikar, Rasika
Kong, Ah-Ng
Kuo, Hsiao-Chen
Li, Shanyi
Peter, Rebecca
Pochung, &
Poiani, George
Shannar, Ahmad
Wang, Lujing
Wu, Renyi
source
Medline; PMC
abstract
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented challenges to the healthcare systems in almost every country around the world. Currently, there are no proven effective vaccines or therapeutic agents against the virus. Current clinical management includes infection prevention and control measures and supportive care including supplemental oxygen and mechanical ventilatory support. Evolving research and clinical data regarding the virologic SARS-CoV-2 suggest a potential list of repurposed drugs with appropriate pharmacological effects and therapeutic efficacies in treating COVID-19 patients. In this review, we will update and summarize the most common and plausible drugs for the treatment of COVID-19 patients. These drugs and therapeutic agents include antiviral agents (remdesivir, hydroxychloroquine, chloroquine, lopinavir, umifenovir, favipiravir, and oseltamivir), and supporting agents (Ascorbic acid, Azithromycin, Corticosteroids, Nitric oxide, IL-6 antagonists), among others. We hope that this review will provide useful and most updated therapeutic drugs to prevent, control, and treat COVID-19 patients until the approval of vaccines and specific drugs targeting SARS-CoV-2.
has issue date
2020-05-11
(
xsd:dateTime
)
bibo:doi
10.1007/s40495-020-00216-7
bibo:pmid
32395418
has license
no-cc
sha1sum (hex)
624560cb35b61e7c2b38aa294d409a8c85644d4f
schema:url
https://doi.org/10.1007/s40495-020-00216-7
resource representing a document's title
An Update on Current Therapeutic Drugs Treating COVID-19
has PubMed Central identifier
PMC7211915
has PubMed identifier
32395418
schema:publication
Curr Pharmacol Rep
resource representing a document's body
covid:624560cb35b61e7c2b38aa294d409a8c85644d4f#body_text
is
schema:about
of
named entity 'acid'
named entity 'potential'
named entity 'oxygen'
named entity 'patients'
named entity 'patients'
named entity 'UMIFENOVIR'
named entity 'ANTIVIRAL AGENTS'
named entity 'SPECIFIC'
named entity 'UPDATE'
named entity 'AZITHROMYCIN'
named entity 'PANDEMIC'
named entity 'USEFUL'
named entity 'CONTROL'
named entity 'TREATING'
named entity 'COUNTRY'
named entity 'ACID'
named entity 'EFFECTIVE'
named entity 'LIST'
named entity 'MEASURES'
named entity 'REVIEW'
named entity 'control'
named entity 'therapeutic drugs'
named entity 'caused'
named entity 'clinical management'
named entity 'patients'
named entity 'COVID'
named entity 'hydroxychloroquine'
named entity 'supportive care'
named entity 'healthcare systems'
named entity 'vaccines'
named entity 'SARS-CoV-2'
named entity 'ventilatory support'
named entity 'therapeutic agents'
named entity 'favipiravir'
named entity 'pharmacological'
named entity 'drugs'
named entity 'cytokines'
named entity 'HIV-1 protease'
named entity 'lysosomes'
named entity 'NL63'
named entity 'organ transplant rejection'
named entity 'COVID'
named entity 'hydroxychloroquine'
named entity 'tocilizumab'
named entity 'C-protein'
named entity 'pulmonary artery pressure'
named entity 'vitamin'
named entity 'HCV'
named entity 'COVID-19 pandemic'
named entity 'arthritis'
named entity 'chest CT scan'
named entity 'alveolar capillaries'
named entity 'nausea'
named entity 'interleukin'
named entity 'IL-6'
named entity 'sirolimus'
named entity 'Chinese University of Hong Kong'
named entity 'remdesivir'
named entity 'IL-1β'
named entity 'expanded access'
named entity 'HIV-1 protease'
named entity 'antiviral therapy'
named entity 'COVID'
named entity 'arthritis'
named entity 'acute respiratory failure'
named entity 'IV infusion'
named entity 'transfusion'
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