About: Structural Analogs of Umifenovir. 1. Synthesis and Biological Activity of Ethyl 5-Hydroxy-1-Methyl-2-(Trans-2-Phenylcyclopropyl)-1H-Indole-3-Carboxylate

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About: Structural Analogs of Umifenovir. 1. Synthesis and Biological Activity of Ethyl 5-Hydroxy-1-Methyl-2-(Trans-2-Phenylcyclopropyl)-1H-Indole-3-Carboxylate Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Structural Analogs of Umifenovir. 1. Synthesis and Biological Activity of Ethyl 5-Hydroxy-1-Methyl-2-(Trans-2-Phenylcyclopropyl)-1H-Indole-3-Carboxylate
Creator	Balzarini, J Kameneva, I Nawrozkij, M Ruchko, E Zakharova, E
source	PMC
abstract	Ethyl 5-hydroxy-1-methyl-2-(trans-2-phenylcyclopropyl)-1H-indole-3-carboxylate is the first prototype of conformationally restricted analogs of umifenovir. It has been prepared using a one-pot method and has undergone an antiviral study.
has issue date	2014-06-08(xsd:dateTime)
bibo:doi	10.1007/s10593-014-1499-y
has license	no-cc
sha1sum (hex)	6303d3932c9be07096c6e3e2956b350d1bdcdd5f
schema:url	https://doi.org/10.1007/s10593-014-1499-y
resource representing a document's title	Structural Analogs of Umifenovir. 1. Synthesis and Biological Activity of Ethyl 5-Hydroxy-1-Methyl-2-(Trans-2-Phenylcyclopropyl)-1H-Indole-3-Carboxylate
has PubMed Central identifier	PMC7088350
schema:publication	Chem Heterocycl Compd (N Y)
resource representing a document's body	covid:6303d3932c9be07096c6e3e2956b350d1bdcdd5f#body_text
is schema:about of	named entity 'HYDROXY' named entity 'STRUCTURAL' named entity '1H-INDOLE-3-CARBOXYLATE' named entity 'ETHYL' named entity 'BIOLOGICAL ACTIVITY' named entity 'ANALOGS' named entity 'UMIFENOVIR' named entity 'SYNTHESIS' named entity 'ANTIVIRAL' named entity 'PROTOTYPE' named entity 'USING' named entity 'UMIFENOVIR' named entity 'METHYL' named entity 'POT METHOD' named entity 'ETHYL' named entity 'STUDY' named entity 'PREPARED' named entity 'RESTRICTED' named entity 'ANALOGS' named entity '1H-INDOLE-3-CARBOXYLATE' named entity 'HYDROXY' named entity 'METHYL' named entity 'conformationally' named entity 'hydroxy' named entity 'trans' named entity 'INDOLE-3-CARBOXYLATE' named entity 'HYDROXY' named entity 'ETHYL' named entity 'reaction mixture' named entity 'chemical reagents' named entity 'trans' named entity 'umifenovir' named entity 'conformationally' named entity 'hexane' named entity '1.08' named entity 'mm Hg' named entity 'induced fit model' named entity 'ester' named entity 'heteroaromatic' named entity 'aminolysis' named entity 'ethyl' named entity 'conformationally' named entity 'acetate' named entity 'carbohydrazide' named entity 'indole' named entity 'Column chromatography' named entity 'cytotoxic' named entity 'umifenovir' named entity 'influenza B virus' named entity 'diastereomers' named entity '1,4-benzoquinone' named entity 'DMSO' named entity 'MgSO' named entity 'chromatographic column' named entity 'trans' named entity 'methyl' named entity 'HCl' named entity 'indole' named entity 'cytotoxicity' named entity 'Ethyl' named entity 'Catholic University at Leuven' named entity 'H3N2' named entity 'absolute ethanol' named entity 'virus' named entity 'thiophenol' named entity 'e-mail' named entity 'mmol' named entity 'pharmacophore' named entity 'umifenovir' named entity 'alkaline' named entity 'trans' named entity 'hydrogen peroxide' named entity '1,3-dioxane' named entity '7.1' named entity 'oxygen' named entity 'MgSO' named entity 'titration' named entity 'chemical structure' named entity 'Joint-stock Company'

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