About: Survival of hospitalized COVID-19 patients in Northern Italy: a population-based cohort study by the ITA-COVID19 Network

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About: Survival of hospitalized COVID-19 patients in Northern Italy: a population-based cohort study by the ITA-COVID19 Network Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Survival of hospitalized COVID-19 patients in Northern Italy: a population-based cohort study by the ITA-COVID19 Network
Creator	Rossi, Paolo Ferroni, Eliana Massari, Marco Bodina, Annalisa Cereda, Danilo Tirani, Marcello Alegiani, Stefania Castrofino, Ambra Cereda, D Crisafulli, Salvatore Da Cas, Roberto Del Castillo, Gabriele Fedeli, Ugo Ferroni, E Formoso, Giulio Grilli, Roberto Grosso, Francesca Ientile, Valentina Ippolito, Francesca Leoni, Olivia Leoni, O Ludergnani, Monica Marino, M Marino, Massimiliano Massari, M Narne, Elena Onder, Graziano Pellizzari, M Pellizzari, Michele Pezzotti, Patrizio Pitter, G Pitter, Gisella Rossi, P Spila Alegiani, S Sultana, Janet Sultana, J Trifirò, G Trifirò, Gianluca Vicentini, Massimo Zorzi, Manuel
Source	MedRxiv
abstract	Background COVID19 case fatality rate in hospitalized patients varies across countries and studies, but reliable estimates specific for age, sex, and comorbidities are needed to design trials for COVID19 interventions. Aim of this study is to provide population-based survival curves of hospitalized COVID19 patients. Methods A cohort study was conducted in Lombardy, Veneto, and Reggio Emilia using COVID19 registries linked to hospital discharge databases containing patient clinical histories. All patients with positive SARS CoV 2 RTPCR test on oral/nasopharyngeal swabs hospitalized from 21st February to 21st April 2020 were identified. Kaplan Meier survival estimates were calculated at 14 and 30 days for death in any setting, stratifying by age, sex and Charlson Index. Findings Overall 42,926 hospitalized COVID19 patients were identified. Patients' median age was 69 years (IQR: 57; 79), 62.6% were males, 69.4% had a Charlson Index of 0. In total, 11,205 (26.1%) patients died over a median follow-up of 24 days (IQR: 10; 35). Survival curves showed that 22.0% of patients died within 14 days and 27.6% within 30 days of hospitalization. Survival was higher in younger patients and in females. Younger patients with comorbidities had a lower survival than older ones with comorbidities. Interpretation Over 27% of hospitalized COVID19 patients died within one month in three areas of Northern Italy that were heavily affected by SARS CoV 2 infection. Such a high fatality rate suggests that trials should focus on survival and have follow-up of at least one month.
has issue date	2020-05-19(xsd:dateTime)
bibo:doi	10.1101/2020.05.15.20103119
has license	medrxiv
sha1sum (hex)	653477dd9925ad9e4b09ea9e4819e9f6cf9dc538
schema:url	https://doi.org/10.1101/2020.05.15.20103119
resource representing a document's title	Survival of hospitalized COVID-19 patients in Northern Italy: a population-based cohort study by the ITA-COVID19 Network
resource representing a document's body	covid:653477dd9925ad9e4b09ea9e4819e9f6cf9dc538#body_text
is schema:about of	named entity 'curves' named entity 'comorbidities' named entity 'TO PROVIDE' named entity 'ESTIMATES' named entity 'POPULATION-BASED' named entity 'INTERVENTIONS' named entity 'hospitalized' named entity 'patients' named entity 'hospitalized' named entity 'COVID-19' named entity 'case fatality rate' named entity 'COVID-19' named entity 'COVID-19' named entity 'COVID' named entity 'Lombardy' named entity 'follow-up' named entity 'National Institute of Health' named entity 'case fatality rates' named entity 'CFR' named entity 'fatality rate' named entity 'comorbidities' named entity 'COVID-19' named entity 'comorbidities' named entity 'Lombardy' named entity 'Reggio Emilia' named entity 'CFR' named entity 'epidemic' named entity 'public health' named entity 'phase II' named entity 'outpatient setting' named entity 'e-mail' named entity 'Charlson index' named entity 'acute respiratory distress syndrome' named entity 'epidemic' named entity 'Emergency Room' named entity 'COVID' named entity 'older patients' named entity 'case fatality rate' named entity 'epidemic' named entity 'phase II trials' named entity 'April 2020' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'COVID-19' named entity 'intensive care unit' named entity 'SARS-CoV-2'

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