About: Damage Control Resuscitation

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Damage Control Resuscitation
Creator	Pereira, Bruno Duchesne, J Duchesne, Juan Fraga, G Pereira Fraga, Gustavo Pereira, B
Source	PMC
abstract	Damage control resuscitation is a resuscitation modality that integrates permissive hypotension, hemostatic resuscitation, and damage control surgery, initially addressing all three components of the “lethal triad”: coagulopathy, acidosis, and hypothermia. Trauma patients predicted to require massive transfusion, administration of fresh frozen plasma, packed red blood cells, and platelets in a 1:1:1 ratio (of individual units) are associated with improved survival and less need for innumerous transfusions. In addition, the evidence so far indicates that the incorporation of these principles into a MTP will also contribute to less transfused units by minimizing variability of transfusion practices. Importantly, fewer units transfused will contribute to fewer complications associated with transfusions. These conclusions will need to be verified, especially with regard to the effect of MTPs incorporating higher ratios of FFP:PRBC:platelets effect on varying mechanism of injury, the timing of transfusions, and the number of units actually transfused. Also recombinant factor VIIa, cryoprecipitate, and tranexamic acid can be considered adjunctive treatments for coagulopathy. Lastly, damage control surgery is a surgical strategy aimed at restoring normal physiology rather than anatomical integrity; however, this component of damage control resuscitation should not be applied in isolation.
has issue date	2013-08-19(xsd:dateTime)
bibo:doi	10.1007/978-88-470-5403-5_3
has license	no-cc
sha1sum (hex)	65d9eac950a0469da5c1974f47c05a361a9b29f1
schema:url	https://doi.org/10.1007/978-88-470-5403-5_3
resource representing a document's title	Damage Control Resuscitation
has PubMed Central identifier	PMC7120797
schema:publication	Trauma Surgery
resource representing a document's body	covid:65d9eac950a0469da5c1974f47c05a361a9b29f1#body_text
is schema:about of	named entity 'NOVEL' named entity 'TRAUMA RESUSCITATION' named entity 'MEDICINE' named entity 'CONFLICTS' named entity 'innovation' named entity 'technical' named entity 'Damage Control' named entity 'exsanguinating trauma' named entity 'Antifibrinolytic' named entity 'fibrinogen' named entity 'MTP' named entity 'Fibrinogen' named entity 'refractory' named entity 'virus transmission' named entity 'hyperfibrinolysis' named entity 'platelets' named entity 'platelet transfusion' named entity 'permissive hypotension' named entity 'lysine' named entity 'hemodynamic' named entity 'class III' named entity 'hemorrhage' named entity 'severely injured' named entity 'coagulopathy' named entity 'multisystem organ failure' named entity 'acidic pH' named entity 'clotting factors' named entity 'Food and Drug Administration' named entity 'FFP' named entity 'clotting factors' named entity 'Glanzmann thrombasthenia' named entity 'adverse effects' named entity 'MTP' named entity 'armamentarium' named entity 'viscus' named entity 'FFP' named entity 'morbidity' named entity 'damage control surgery' named entity 'intravenously' named entity 'advances in medicine' named entity 'isotonic' named entity 'permissive hypotension' named entity 'PRBC' named entity 'tranexamic acid' named entity 'coagulopathy' named entity 'Hemostatic' named entity 'PRBC' named entity 'PRBC' named entity 'Recombinant factor VIIa' named entity 'torso' named entity 'coagulopathy' named entity 'retrospective cohort study' named entity 'trauma patients' named entity 'rFVIIa' named entity 'blood components' named entity 'class III' named entity 'abdomen' named entity 'MTP' named entity 'PRBCs' named entity 'procoagulant' named entity 'erythrocytes' named entity 'platelets' named entity 'fibrin' named entity 'ventilator' named entity 'mmol/l' named entity 'critically ill patients' named entity 'coagulation' named entity 'plasma' named entity 'calcium' named entity 'organ' named entity 'fluid resuscitation' named entity 'diagnostic tests' named entity 'traumatic brain injury' named entity 'topical negative pressure' named entity 'permissive hypotension' named entity 'severe hemorrhage' named entity 'trauma patients' named entity 'Permissive hypotension'

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