About: SARS-CoV-2-specific ELISA development

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	SARS-CoV-2-specific ELISA development
Creator	Alter, Galit Ryan, Edward Charles, Richelle Baden, Lindsey Astudillo, Michael Atyeo, Caroline Balazs, Alejandro Feldman, Jared Fischinger, Stephanie Hauser, Blake Loos, Carolin Miller, Tyler Nilles, Eric Slein, Matthew Wesemann, Duane Yang, Diane Caradonna, Tim Lauffenburger, Douglas Beltran, Wilfredo Luedemann, Corinne Murali, Mandakolathur Roy, Vicky Gerino Astudillo, Michael John Lafrate, A Lafrate, A
source	Elsevier; Medline; PMC
abstract	Critical to managing the spread of COVID-19 is the ability to diagnose infection and define the acquired immune response across the population. While genomic tests for the novel Several Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) detect the presence of viral RNA for a limited time frame, when the virus is shed in the upper respiratory tract, tests able to define exposure and infection beyond this short window of detectable viral replication are urgently needed. Following infection, antibodies are generated within days, providing a durable read-out and archive of exposure and infection. Several antibody tests have emerged to diagnose SARS-CoV-2. Here we report on a qualified quantitative ELISA assay that displays all the necessary characteristics for high-throughput sample analysis. Collectively, this test offers a quantitative opportunity to define both exposure and levels of immunity to SARS-CoV-2.
has issue date	2020-08-08(xsd:dateTime)
bibo:doi	10.1016/j.jim.2020.112832
bibo:pmid	32780998
has license	no-cc
sha1sum (hex)	66259aab68db473e750f671422519eb40e398186
schema:url	https://doi.org/10.1016/j.jim.2020.112832
resource representing a document's title	SARS-CoV-2-specific ELISA development
has PubMed Central identifier	PMC7414735
has PubMed identifier	32780998
schema:publication	J Immunol Methods
resource representing a document's body	covid:66259aab68db473e750f671422519eb40e398186#body_text
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