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About:
Cardiovascular manifestations in severe and critical patients with COVID‐19
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
wasabi.inria.fr
associated with source
document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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Attributes
Values
type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Cardiovascular manifestations in severe and critical patients with COVID‐19
Creator
Xu, Lili
Ge, Junbo
Di,
Zhu,
Chen, Qingxing
Dai, Yongbin
Di, Wencheng
Ling, Yunlong
Mao, Jiahao
Qian, Juying
Zhu, Wenqing
Junbo Ge,
Source
Medline; PMC; WHO
abstract
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) could cause virulent infection leading to Corona Virus Disease 2019 (COVID‐19)‐related pneumonia as well as multiple organ injuries. HYPOTHESIS: COVID‐19 infection may result in cardiovascular manifestations leading to worse clinical outcome. METHODS: Fifty four severe and critical patients with confirmed COVID‐19 were enrolled. Risk factors predicting the severity of COVID‐19 were analyzed. RESULTS: Of the 54 patients (56.1 ± 13.5 years old, 66.7% male) with COVID‐19, 39 were diagnosed as severe and 15 as critical cases. The occurrence of diabetes, the level of D‐dimer, inflammatory and cardiac markers in critical cases were significantly higher. Troponin I (TnI) elevation occurred in 42.6% of all the severe and critical patients. Three patients experienced hypotension at admission and were all diagnosed as critical cases consequently. Hypotension was found in one severe case and seven critical cases during hospitalization. Sinus tachycardia is the most common type of arrythmia and was observed in 23 severe patients and all the critical patients. Atrioventricular block and ventricular tachycardia were observed in critical patients at end stage while bradycardia and atrial fibrillation were less common. Mild pericardial effusion was observed in one severe case and five critical cases. Three critical cases suffered new onset of heart failure. Hypotension during treatment, severe myocardial injury and pericardial effusion were independent risk factors predicting the critical status of COVID‐19 infection. CONCLUSION: This study has systemically observed the impact of COVID‐19 on cardiovascular system, including myocardial injury, blood pressure, arrythmia and cardiac function in severe and critical cases. Monitoring of vital signs and cardiac function of COVID‐19 patients and applying potential interventions especially for those with hypotension during treatment, severe myocardial injury or pericardial effusion, is of vital importance.
has issue date
2020-06-20
(
xsd:dateTime
)
bibo:doi
10.1002/clc.23384
bibo:pmid
32562427
has license
cc-by
sha1sum (hex)
67e3843d0ed75ccd863dc14990f73b226a63f7ba
schema:url
https://doi.org/10.1002/clc.23384
resource representing a document's title
Cardiovascular manifestations in severe and critical patients with COVID‐19
has PubMed Central identifier
PMC7323347
has PubMed identifier
32562427
schema:publication
Clin Cardiol
resource representing a document's body
covid:67e3843d0ed75ccd863dc14990f73b226a63f7ba#body_text
is
schema:about
of
named entity 'diabetes'
named entity 'Methods'
named entity 'Hypotension'
named entity 'COVID-19'
named entity 'COVID-19'
named entity 'ANALYZED'
named entity 'RELATED'
named entity 'DURING TREATMENT'
named entity '66.7'
named entity 'CONFIRMED'
covid:arg/67e3843d0ed75ccd863dc14990f73b226a63f7ba
named entity 'cases'
named entity 'hypotension'
named entity 'critical'
named entity 'Risk factors'
named entity 'COVID-19'
named entity 'observed'
named entity 'critical'
named entity 'critical'
named entity 'elevation'
named entity 'cases'
named entity 'infection'
named entity 'patients'
named entity 'Corona'
named entity 'pneumonia'
named entity 'patients'
named entity 'independent'
named entity 'critical'
named entity 'COVID-19'
named entity 'pericardial effusion'
named entity 'virulent'
named entity 'COVID-19'
named entity 'COVID'
named entity 'Risk factors'
named entity 'pneumonia'
named entity 'heart failure'
named entity 'end stage'
named entity 'D-dimer'
named entity 'cardiovascular'
named entity 'cardiac'
named entity 'pericardial effusion'
named entity 'serum level'
named entity 'blood pressure'
named entity 'hypotension'
named entity 'mitral valve replacement'
named entity 'cellular immune'
named entity 'Clinical features'
named entity 'cardiovascular'
named entity 'pericardial effusion'
named entity 'Blood pressure'
named entity 'WBC'
named entity 'sample size'
named entity 'pathological evidence'
named entity 'risk factor'
named entity 'Cardiac biomarkers'
named entity 'COVID'
named entity 'hypotension'
named entity 'blood pressure'
named entity 'eardrum'
named entity 'diastolic blood pressure'
named entity 'Hypotension'
named entity 'acute kidney injury'
named entity 'prognosis'
named entity 'ACE2'
named entity 'cardiologists'
named entity 'myocardial injury'
named entity 'cardiovascular'
named entity 'Monitoring of vital signs'
named entity 'Hypotension'
named entity 'Sinus tachycardia'
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