About: The ongoing COVID-19 epidemic in Minas Gerais, Brazil: insights from epidemiological data and SARS-CoV-2 whole genome sequencing.

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About: The ongoing COVID-19 epidemic in Minas Gerais, Brazil: insights from epidemiological data and SARS-CoV-2 whole genome sequencing. Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The ongoing COVID-19 epidemic in Minas Gerais, Brazil: insights from epidemiological data and SARS-CoV-2 whole genome sequencing.
Creator	Giovanetti, Marta Fonseca, Vagner Lima, Mauricio Alcantara, Junior Carlos, Luiz Lourenço, José Adelino, Talita Agudo, Marilda Aparecida, Marluce Azevedo, De Bispo De Filippis, Ana Campelo De Albuquerque, Carlos De Jesus, Ronaldo Duarte, Clara Fabri, Felicio, Katlin Franco, Cristiane Gutemberg, Thales Holmes, Ed-Ward Iani, Felipe Luiz De Abreu, André Oliveira, As-10 Ramalho, Dario Ribeiro, Adriana Salgado, Álvaro Santos, Souza Silva, Ferreira Teixeira De Siqueira, Mendonça Tulio De Oliveira, ; Vinicius, Marcos Vitor Barbosa 4 Da Costa, Alana Xavier, Joilson Zoboli, Soares
Source	MedRxiv
abstract	The recent emergence of a previously unknown coronavirus (SARS-CoV-2), first confirmed in the city of Wuhan in China in December 2019, has caused serious public health and economic issues due to its rapid dissemination worldwide. Although 61,888 confirmed cases had been reported in Brazil by 28 April 2020, little was known about the SARS-CoV-2 epidemic in the country. To better understand the recent epidemic in the second most populous state in southeast Brazil (Minas Gerais, MG), we looked at existing epidemiological data from 3 states and sequenced 40 complete genomes from MG cases using Nanopore. We found evidence of multiple independent introductions from outside MG, both from genome analyses and the overly dispersed distribution of reported cases and deaths. Epidemiological estimates of the reproductive number using different data sources and theoretical assumptions all suggest a reduction in transmission potential since the first reported case, but potential for sustained transmission in the near future. The estimated date of introduction in Brazil was consistent with epidemiological data from the first case of a returning-traveler from Lombardia, Italy. These findings highlight the unique reality of MGs epidemic and reinforce the need for real-time and continued genomic surveillance strategies as a way of understanding and therefore preparing against the epidemic spread of emerging viral pathogens.
has issue date	2020-05-11(xsd:dateTime)
bibo:doi	10.1101/2020.05.05.20091611
has license	medrxiv
sha1sum (hex)	67fb1261c84d51ce97baa592c10feff6855eb347
schema:url	https://doi.org/10.1101/2020.05.05.20091611
resource representing a document's title	The ongoing COVID-19 epidemic in Minas Gerais, Brazil: insights from epidemiological data and SARS-CoV-2 whole genome sequencing.
resource representing a document's body	covid:67fb1261c84d51ce97baa592c10feff6855eb347#body_text
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