About: Detection of human rhinoviruses in the lower respiratory tract of lung transplant recipients

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About: Detection of human rhinoviruses in the lower respiratory tract of lung transplant recipients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Detection of human rhinoviruses in the lower respiratory tract of lung transplant recipients
Creator	Bergallo, Massimiliano Astegiano, Sara Cavallo, Rossana Costa, Cristina Sidoti, Francesca Terlizzi, Maria Gambarino, Stefano Solidoro, Paolo Curtoni, Antonio Simeone, Salvatore
source	Medline; PMC
abstract	The occurrence of human rhinoviruses (HRV) and its relationship to clinical and histopathological findings were investigated in 127 bronchoalveolar lavage specimens from 36 lung transplant recipients by real-time RT-PCR. In addition, 286 samples from 235 other immunocompromised and immunocompetent patients were also studied. HRV was detected in 41.7% of lung transplant recipients vs 14.5% of other patients (p < 0.0001), and no differences in viral load were observed. Acute respiratory insufficiency was found in 15 cases, three of which were HRV positive (viral load, 6.3x10(6) RNA copies/ml in one patient with chronic graft dysfunction). A diagnosis of pneumonia was made in 10 out of 127 cases, two of which were HRV positive (viral load, 10(3)-10(4) in cases of co-infection). Acute rejection was diagnosed in 12 cases, three of which were HRV positive (viral load, 10(3) in two cases of co-infection and 10(5) in a single infection). HRV infection may involve the lower respiratory tract, particularly in the presence of an impaired pulmonary background, such as a transplanted lung. Clinical evaluation should take into account the viral load, with a load of >10(5) possibly being associated with clinical symptoms, although lower loads can be detected in both symptomatic and asymptomatic patients.
has issue date	2011-04-03(xsd:dateTime)
bibo:doi	10.1007/s00705-011-0986-z
bibo:pmid	21461933
has license	no-cc
sha1sum (hex)	68c9063f9e54a894fc8bedb4424d1d9d3ce69318
schema:url	https://doi.org/10.1007/s00705-011-0986-z
resource representing a document's title	Detection of human rhinoviruses in the lower respiratory tract of lung transplant recipients
has PubMed Central identifier	PMC7087099
has PubMed identifier	21461933
schema:publication	Arch Virol
resource representing a document's body	covid:68c9063f9e54a894fc8bedb4424d1d9d3ce69318#body_text
is schema:about of	named entity 'immunocompetent' named entity 'chronic' named entity 'patients' named entity 'respiratory tract' named entity 'positive' named entity 'RNA' named entity 'RT-PCR' named entity 'observed' named entity 'cases' named entity 'immunocompromised' named entity 'viral load' named entity 'HRV' named entity 'RNA' named entity 'real-time RT-PCR' named entity 'respiratory symptoms' named entity 'coinfected' named entity 'dyspnea' named entity 'HRV' named entity 'RNA' named entity '1, 2' named entity 'tracheobronchial tree' named entity 'co-infection' named entity 'mycophenolate mofetil' named entity 'HRV' named entity 'HRV' named entity 'upper respiratory tract' named entity 'HRV' named entity 'co-infection' named entity 'kidney' named entity 'viral load' named entity 'valganciclovir' named entity 'RNA' named entity 'common cold' named entity 'real-time PCR' named entity 'RNA' named entity 'cough' named entity 'body weight' named entity 'immunocompromised patients' named entity 'bronchiolitis' named entity 'Lung Transplantation' named entity 'Pseudomonas aeruginosa' named entity 'lung' named entity 'respiratory tract infection' named entity 'signs and/or symptoms' named entity 'HRV' named entity 'herpesvirus' named entity 'lower respiratory tract' named entity 'HIV' named entity 'Histopathological' named entity 'cystic fibrosis' named entity 'long-term' named entity 'signs/symptoms' named entity 'work-up' named entity 'HRV' named entity 'lower respiratory tract' named entity 'Periodic acid-Schiff' named entity 'lower respiratory tract' named entity 'HHV-6' named entity 'tacrolimus' named entity 'lower respiratory tract' named entity 'HRV' named entity 'immunocompromised patients' named entity 'follow-up' named entity 'clinical symptoms' named entity 'HCMV' named entity 'respiratory symptoms' named entity 'HRV' named entity 'HRV' named entity 'lower respiratory tract' named entity 'clinical symptoms' named entity 'lower respiratory tract' named entity 'respiratory insufficiency'

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