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About:
Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report
Creator
Carrier, Marc
Doerschug, Kevin
Jimenez, David
Brosnahan, Shari
Collen, Jacob
Rali, Parth
Carrier Md, Marc
Holley, Aaron
Legal, Gregoire
Moores, Lisa
Tritschler, Tobias
Wells, Philip
source
Elsevier; Medline; PMC
abstract
Abstract: Background Emerging evidence shows that severe COVID-19 can be complicated by a significant coagulopathy, that likely manifests in the form of both microthrombosis and venous thromboembolism (VTE). This recognition has led to the urgent need for practical guidance regarding prevention, diagnosis, and treatment of VTE. Methods A group of approved panelists developed key clinical questions by using the PICO (population, intervention, comparator, and outcome) format that addressed urgent clinical questions regarding the prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19. MEDLINE (via PubMed or Ovid), Embase and Cochrane Controlled Register of Trials were systematically searched for relevant literature and references were screened for inclusion. Validated evaluation tools were used to grade the level of evidence to support each recommendation. When evidence did not exist, guidance was developed based on consensus using the modified Delphi process. Results The systematic review and critical analysis of the literature based on13 PICO questions resulted in 22 statements. Very little evidence exists in the COVID-19 population. The panel thus used expert consensus and existing evidence-based guidelines to craft the guidance statements. Conclusions The evidence on the optimal strategies to prevent, diagnose, and treat venous thromboembolism in patients with COVID-19 is sparse, but rapidly evolving.
has issue date
2020-06-02
(
xsd:dateTime
)
bibo:doi
10.1016/j.chest.2020.05.559
bibo:pmid
32502594
has license
els-covid
sha1sum (hex)
6ae323502b8d39790a7e0bc468f141f63bd7d279
schema:url
https://doi.org/10.1016/j.chest.2020.05.559
resource representing a document's title
Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report
has PubMed Central identifier
PMC7265858
has PubMed identifier
32502594
schema:publication
Chest
resource representing a document's body
covid:6ae323502b8d39790a7e0bc468f141f63bd7d279#body_text
is
schema:about
of
named entity 'patients'
named entity 'venous thromboembolism'
named entity 'venous thromboembolism'
named entity 'COVID-19'
named entity 'anticoagulation'
named entity 'COVID'
named entity 'DVT'
named entity 'VTE'
named entity 'vitamin K antagonist'
named entity 'UFH'
named entity 'septic shock'
named entity 'anticoagulant'
named entity 'D-dimer'
named entity '2.04'
named entity 'retrospective review'
named entity 'heart strain'
named entity 'VTE'
named entity 'edoxaban'
named entity 'nursing staff'
named entity 'thrombolytic therapy'
named entity 'endothelial'
named entity 'anticoagulant'
named entity 'COVID'
named entity 'UFH'
named entity 'anticoagulants'
named entity 'COVID'
named entity 'VTE'
named entity 'prophylaxis'
named entity 'vitamin K antagonists'
named entity 'disseminated intravascular coagulation'
named entity 'randomized controlled trials'
named entity 'critically ill'
named entity 'acute respiratory distress syndrome'
named entity 'DIC'
named entity 'anticoagulant'
named entity 'anticoagulant'
named entity 'severe respiratory failure'
named entity 'blood pressure'
named entity 'anticoagulant'
named entity 'thrombosis'
named entity 'randomized trials'
named entity 'COVID'
named entity 'UFH'
named entity 'anticoagulant'
named entity 'DIC'
named entity 'VTE'
named entity 'thromboprophylaxis'
named entity 'literature search'
named entity 'anticoagulant'
named entity 'LMWH'
named entity 'Cox proportional hazards model'
named entity 'thromboprophylaxis'
named entity 'antiviral agents'
named entity 'randomized trials'
named entity 'cumulative incidence'
named entity 'COVID'
named entity 'Wuhan'
named entity 'UFH'
named entity 'low-molecular-weight heparin'
named entity 'DOACs'
named entity 'LMWH'
named entity 'risk factor'
named entity 'proximal'
named entity 'Unfractionated heparin'
named entity 'fondaparinux'
named entity 'VTE'
named entity 'COVID'
named entity 'ICU'
named entity 'LMWH'
named entity 'VTE'
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