About: Significance of serology testing to assist timely diagnosis of SARS-CoV-2 infections: implication from a family cluster

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Significance of serology testing to assist timely diagnosis of SARS-CoV-2 infections: implication from a family cluster
Creator	Xu, Jun Du, Tiekuan Xu, Yan Zhu, Huadong Han, Yang Li, Taisheng Xiao, Meng Wang, Mengzhao Xu, Yingchun Liu, Xinchao Yang, Qiwen Xu, Shengyong
Source	Medline; PMC
abstract	Confirmative diagnosis of SARS-CoV-2 infections has been challenged due to unsatisfactory positive rate of molecular assays. Here we identified a family cluster of SARS-CoV-2 infections, with five of six family members were SARS-CoV-2-specific immunoglobin serology testing positive, while molecular assays only detected two of this five patients even repeated twice. We comprehensively analyzed this familial cluster of cases based on the clinical characteristics, chest CT images, SARS-CoV-2 molecular detection results, and serology testing results. At last, two patients were diagnosed with COVID-19, two were suspected of COVID-19, and two were considered close contacts. Our results emphasized the significance of serology testing to assist timely diagnosis of SARS-CoV-2 infections, especially for COVID-19 close contacts screening.
has issue date	2020-05-13(xsd:dateTime)
bibo:doi	10.1080/22221751.2020.1752610
bibo:pmid	32286155
has license	cc-by
sha1sum (hex)	6b1ec9b2db570243ec9ecb61b1ef51d538e2eaef
schema:url	https://doi.org/10.1080/22221751.2020.1752610
resource representing a document's title	Significance of serology testing to assist timely diagnosis of SARS-CoV-2 infections: implication from a family cluster
has PubMed Central identifier	PMC7269047
has PubMed identifier	32286155
schema:publication	Emerg Microbes Infect
resource representing a document's body	covid:6b1ec9b2db570243ec9ecb61b1ef51d538e2eaef#body_text
is schema:about of	named entity 'screening' named entity 'COVID-19' named entity 'COVID-19' named entity 'SARS-CoV-2' named entity 'OUR' named entity 'BASED' named entity 'SEROLOGY' named entity 'IMMUNOGLOBIN' named entity 'CLUSTER OF CASES' named entity 'SCREENING' named entity 'TIMELY' named entity 'TWICE' named entity 'SARS-CoV-2' named entity 'patients' named entity 'COVID-19' named entity 'assays' named entity 'diagnosis' named entity 'serology' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'COVID-19' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'COVID-19' named entity 'COVID' named entity 'SARS-CoV' named entity 'Beijing' named entity 'China' named entity 'immunoglobin' named entity 'COVID' named entity 'serology' named entity 'chest CT' named entity 'COVID' named entity 'IgG' named entity 'symptom' named entity 'reverse-transcriptase' named entity 'viral pneumonia' named entity 'Peking Union Medical College Hospital' named entity 'COVID-19 pandemic' named entity 'Chest CT' named entity 'SARS-CoV-2' named entity 'respiratory symptoms' named entity 'COVID' named entity 'molecular testing' named entity 'asymptomatic infection' named entity 'COVID-19' named entity 'Serology testing' named entity 'false-negative' named entity 'CT scanning' named entity 'viral pneumonia' named entity 'COVID' named entity 'molecular testing' named entity 'SARS-CoV-2' named entity 'asymptomatic' named entity 'Wuhan' named entity 'serology' named entity 'RNA' named entity 'ground-glass opacity' named entity 'RT-PCR' named entity 'first-line' named entity 'infection' named entity 'infection control' named entity 'SARS-CoV-2' named entity 'COVID-19' named entity 'IgM' named entity 'SARS-CoV-2' named entity 'viral pneumonia' named entity 'enzyme-linked immunosorbent assay' named entity 'Beijing' named entity 'COVID'

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