About: Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years
Creator	Cardosa, Mary Gias, Edna Kiyu, Andrew Leong, Yee-Wei Ong, Flora Perera, David Podin, Yuwana Teo, Bibiana Wee, Thian-Yew Yao, Sik-Chi Yao, Sik-King Yee, Siew-Fung Yusof, Mohd Abang, Jalan Openg, Haji Taha Arif, Mohd
source	PMC
abstract	BACKGROUND: A major outbreak of human enterovirus 71-associated hand, foot and mouth disease in Sarawak in 1997 marked the beginning of a series of outbreaks in the Asia Pacific region. Some of these outbreaks had unusually high numbers of fatalities and this generated much fear and anxiety in the region. METHODS: We established a sentinel surveillance programme for hand, foot and mouth disease in Sarawak, Malaysia, in March 1998, and the observations of the first 7 years are described here. Virus isolation, serotyping and genotyping were performed on throat, rectal, vesicle and other swabs. RESULTS: During this period Sarawak had two outbreaks of human enterovirus 71, in 2000 and 2003. The predominant strains circulating in the outbreaks of 1997, 2000 and 2003 were all from genogroup B, but the strains isolated during each outbreak were genetically distinct from each other. Human enterovirus 71 outbreaks occurred in a cyclical pattern every three years and Coxsackievirus A16 co-circulated with human enterovirus 71. Although vesicles were most likely to yield an isolate, this sample was not generally available from most cases and obtaining throat swabs was thus found to be the most efficient way to obtain virological information. CONCLUSION: Knowledge of the epidemiology of human enterovirus 71 transmission will allow public health personnel to predict when outbreaks might occur and to plan interventions in an effective manner in order to reduce the burden of disease.
has issue date	2006-07-07(xsd:dateTime)
bibo:doi	10.1186/1471-2458-6-180
bibo:pmid	16827926
has license	cc-by
sha1sum (hex)	6bbbd25c11b320bdd509a9c76417ed4045349708
schema:url	https://doi.org/10.1186/1471-2458-6-180
resource representing a document's title	Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years
has PubMed Central identifier	PMC1543637
has PubMed identifier	16827926
schema:publication	BMC Public Health
resource representing a document's body	covid:6bbbd25c11b320bdd509a9c76417ed4045349708#body_text
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