About: A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses

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About: A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses
Creator	Jin, Dong-Yan Chan, Chi-Ping Fung, Sin-Yee Yuen, Kit-San Ye, Zi-Wei
Source	Medline; PMC
abstract	World Health Organization has declared the ongoing outbreak of coronavirus disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus was named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Committee on Taxonomy of Viruses. Human infection with SARS-CoV-2 leads to a wide range of clinical manifestations ranging from asymptomatic, mild, moderate to severe. The severe cases present with pneumonia, which can progress to acute respiratory distress syndrome. The outbreak provides an opportunity for real-time tracking of an animal coronavirus that has just crossed species barrier to infect humans. The outcome of SARS-CoV-2 infection is largely determined by virus-host interaction. Here, we review the discovery, zoonotic origin, animal hosts, transmissibility and pathogenicity of SARS-CoV-2 in relation to its interplay with host antiviral defense. A comparison with SARS-CoV, Middle East respiratory syndrome coronavirus, community-acquired human coronaviruses and other pathogenic viruses including human immunodeficiency viruses is made. We summarize current understanding of the induction of a proinflammatory cytokine storm by other highly pathogenic human coronaviruses, their adaptation to humans and their usurpation of the cell death programmes. Important questions concerning the interaction between SARS-CoV-2 and host antiviral defence, including asymptomatic and presymptomatic virus shedding, are also discussed.
has issue date	2020-03-14(xsd:dateTime)
bibo:doi	10.1080/22221751.2020.1736644
bibo:pmid	32172672
has license	cc-by
sha1sum (hex)	6bc503470575d86c809d73642019be355d05dbaf
schema:url	https://doi.org/10.1080/22221751.2020.1736644
resource representing a document's title	A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses
has PubMed Central identifier	PMC7103735
has PubMed identifier	32172672
schema:publication	Emerg Microbes Infect
resource representing a document's body	covid:6bc503470575d86c809d73642019be355d05dbaf#body_text
is schema:about of	named entity 'HOST' named entity 'PATHOGENIC' named entity 'human immunodeficiency viruses' named entity 'coronavirus' named entity 'species barrier' named entity 'human coronaviruses' named entity 'discovery' named entity 'host' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'ONGOING' named entity 'DISCOVERY' named entity 'INCLUDING' named entity 'HIGHLY' named entity 'BARRIER' named entity 'MILD' named entity 'OUTBREAK' named entity 'SARS-COV-2' named entity 'TRACKING' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2' named entity 'WIDE' named entity 'MODERATE TO SEVERE' named entity 'CORONAVIRUS' named entity 'ORIGIN' named entity 'JUST' named entity 'THEIR' named entity 'CELL DEATH' named entity 'CROSSED' named entity 'VIRUS SHEDDING' named entity 'RELATION' named entity 'RANGE' named entity 'NAMED' named entity 'PRESENT' named entity 'OUTCOME' named entity 'CASES' named entity 'PROVIDES' named entity 'COMPARISON' named entity 'CLINICAL MANIFESTATIONS' named entity 'WAR' named entity 'OF-' named entity 'TUG' named entity 'HERE' named entity 'SPECIES' named entity 'SARS-COV' named entity 'ACQUIRED' named entity 'CYTOKINE STORM' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'IMMUNODEFICIENCY VIRUSES' named entity 'ANTIVIRAL' named entity 'TO INFECT' named entity 'REVIEW' named entity 'SEVERE' named entity 'INDUCTION' named entity 'UNDERSTANDING' named entity 'VIRUSES' named entity 'ZOONOTIC' named entity 'CORONAVIRUS DISEASE 2019' named entity 'CORONAVIRUSES' named entity 'HUMANS' named entity 'ASYMPTOMATIC' named entity 'HOSTS' named entity 'PROGRESS' named entity 'HUMAN' named entity 'PATHOGENICITY' named entity 'PATHOGENIC' named entity 'CURRENT' named entity 'TAXONOMY' named entity 'ADAPTATION' named entity 'VIRUS-HOST INTERACTION' named entity 'ACUTE RESPIRATORY DISTRESS SYNDROME' named entity 'INFECTION' named entity 'DEFENSE' named entity 'INTERACTION' named entity 'LARGELY' named entity 'HOST' named entity 'WORLD HEALTH ORGANIZATION' named entity 'VIRUS' named entity 'ITS'

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