About: The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis

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About: The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis
Creator	Park, Joo-Hyun Cho, Kim, Kim, Bo Kim, Hae Jang, ·wook Lee, ·jeongjun Lim, ·yun-Sung Park, Seok-Won
Source	Medline; PMC; WHO
abstract	OBJECTIVES: The objectives of this study were to identify the clinical features and chest computed tomography (CT) findings of coronavirus disease 2019 (COVID-19) patients and to compare the characteristics of patients diagnosed in Wuhan and in other areas of China by integrating the findings reported in previous studies. METHODS: We conducted a proportion meta-analysis to integrate the results of previous studies identified in online databases, and subsequently compared the overlapping of 95% confidence intervals (CIs) between locations of diagnosis. The heterogeneity of the results of the included studies was also demonstrated. RESULTS: Nine studies with level IV evidence were considered to be eligible for the meta-analysis, and a comparative analysis was only possible between patients diagnosed in Wuhan and outside of Wuhan in China. Fever (84.8%; 95% CI, 78.5% to 90.1%) was identified as the most common clinical manifestation in all COVID-19 patients, and signs of respiratory infection were also frequently present in these patients. When comparing the clinical features according to the location of diagnosis, fever and dyspnea were less frequent in patients diagnosed outside of Wuhan (fever: 78.1%; 95% CI, 73.2% to 82.7%; dyspnea: 3.80%; 95% CI, 0.13% to 12.22%) than in patients diagnosed in Wuhan (fever: 91.7%; 95% CI, 88.0% to 94.8%; dyspnea: 21.1%; 95% CI, 13.2% to 30.3%). The chest CT findings exhibited no significant differences between the groups. CONCLUSION: Fever was found to be the most common symptom in COVID-19, and respiratory infection signs were also commonly present. Fever and dyspnea were less frequently observed in the patients diagnosed outside of Wuhan, which should be considered in COVID-19 screening programs. These results may be attributable to the earlier diagnosis of the disease and the younger age of patients outside of Wuhan although further analysis is needed. The role of chest CT in COVID-19 diagnosis is inconclusive based on this study.
has issue date	2020-05-01(xsd:dateTime)
bibo:doi	10.21053/ceo.2020.00570
bibo:pmid	32434310
has license	cc-by-nc
sha1sum (hex)	6c67581ce68c56cde4844516de17f65a17391229
schema:url	https://doi.org/10.21053/ceo.2020.00570
resource representing a document's title	The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis
has PubMed Central identifier	PMC7248616
has PubMed identifier	32434310
schema:publication	Clin Exp Otorhinolaryngol
resource representing a document's body	covid:6c67581ce68c56cde4844516de17f65a17391229#body_text
is schema:about of	named entity 'patients' named entity 'CORONAVIRUS DISEASE 2019' named entity 'compare' named entity 'chest' named entity 'China' named entity 'Proportion' named entity 'Chest' named entity 'Wuhan' named entity 'clinical features' named entity 'China' named entity 'Computed Tomography' named entity 'Coronavirus Disease 2019' named entity 'Wuhan' named entity 'chest CT' named entity 'Wuhan' named entity 'fever' named entity 'COVID' named entity 'fever' named entity 'infection' named entity 'COVID' named entity 'fever' named entity 'COVID' named entity 'symptom' named entity 'otorhinolaryngologists' named entity '95% CI' named entity 'fever' named entity 'cough' named entity 'nasopharyngeal' named entity 'United States' named entity 'gustatory' named entity 'epidemiological' named entity 'COVID-19 pandemic' named entity 'reverse transcription-polymerase chain reaction' named entity 'observational studies' named entity 'lungs' named entity 'China' named entity 'Microsoft Excel' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'Wuhan' named entity 'Wuhan' named entity 'meta-analysis' named entity 'COVID' named entity 'infectious disease' named entity '95% CI' named entity 'Europe' named entity 'spread of the disease' named entity 'rRT-PCR' named entity 'myalgia' named entity 'fever' named entity 'rRT-PCR' named entity 'COVID-19' named entity 'chest CT' named entity 'chest CT' named entity 'Wuhan' named entity 'shortness of breath' named entity 'Wuhan' named entity '95% confidence interval' named entity 'epidemiological' named entity 'South Korea' named entity 'Europe' named entity 'dyspnea' named entity 'Microsoft Excel' named entity 'China' named entity 'COVID-19' named entity 'difficulty in breathing' named entity 'epidemiological' named entity 'fever' named entity 'sputum' named entity 'COVID-19' named entity 'Wuhan' named entity 'symptom' named entity 'cough' named entity 'caused by COVID-19'

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