About: Molecular biology of severe acute respiratory syndrome coronavirus

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Molecular biology of severe acute respiratory syndrome coronavirus
Creator	Ziebuhr, John
Source	Elsevier; Medline; PMC
abstract	The worldwide epidemic of severe acute respiratory syndrome (SARS) in 2003 was caused by a novel coronavirus called SARS-CoV. Coronaviruses and their closest relatives possess extremely large plus-strand RNA genomes and employ unique mechanisms and enzymes in RNA synthesis that separate them from all other RNA viruses. The SARS epidemic prompted a variety of studies on multiple aspects of the coronavirus replication cycle, yielding both rapid identification of the entry mechanisms of SARS-CoV into host cells and valuable structural and functional information on SARS-CoV proteins. These recent advances in coronavirus research have important implications for the development of anti-SARS drugs and vaccines.
has issue date	2004-07-28(xsd:dateTime)
bibo:doi	10.1016/j.mib.2004.06.007
bibo:pmid	15358261
has license	no-cc
sha1sum (hex)	6cb8557be9e1494c669f0e1d0ab5e84a88239a14
schema:url	https://doi.org/10.1016/j.mib.2004.06.007
resource representing a document's title	Molecular biology of severe acute respiratory syndrome coronavirus
has PubMed Central identifier	PMC7108451
has PubMed identifier	15358261
schema:publication	Curr Opin Microbiol
resource representing a document's body	covid:6cb8557be9e1494c669f0e1d0ab5e84a88239a14#body_text
is schema:about of	named entity 'severe acute respiratory syndrome coronavirus' named entity 'biology' named entity 'severe acute respiratory syndrome coronavirus' named entity 'RDRP' named entity 'RNA-DEPENDENT RNA POLYMERASE' named entity 'PL2' named entity 'SARS' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS' named entity 'OPEN READING FRAME' named entity 'SARS-COV' named entity 'ORF' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS' named entity 'MOLECULAR BIOLOGY' named entity 'URIDYLATE-SPECIFIC ENDORIBONUCLEASE' named entity 'PROTEASE 2' named entity 'PRO' named entity 'LIKE' named entity 'REGULATING' named entity 'TRANSCRIPTION' named entity 'SEQUENCE' named entity 'MRNA' named entity 'REPEAT' named entity 'PAPAIN' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'TRS' named entity 'HUMAN CORONAVIRUS 229E' named entity 'protease' named entity 'worldwide epidemic' named entity 'N-terminus' named entity 'glycoproteins' named entity 'coronavirus' named entity 'protease' named entity 'clone' named entity 'coronavirus' named entity 'RdRp' named entity 'endemic in humans' named entity 'Arteriviridae' named entity 'coronaviruses' named entity 'exonuclease' named entity 'transmembrane domain' named entity 'phosphatase' named entity 'active site' named entity 'protease' named entity 'protein' named entity 'SARS-CoV' named entity 'protease' named entity 'mRNAs' named entity 'ExoN' named entity 'SARS-CoV' named entity 'petal' named entity 'C-terminus' named entity 'double-stranded' named entity 'mRNAs' named entity 'SARS outbreak' named entity 'Vietnam' named entity 'leader sequence' named entity 'SARS-CoV' named entity 'ORF' named entity 'substrates' named entity 'virus' named entity 'SARS-CoV' named entity 'Guangdong' named entity 'papain' named entity 'nonstructural proteins' named entity 'nucleoside analog' named entity 'ADP-ribose' named entity 'leader sequence' named entity 'processively' named entity 'infection control' named entity 'nucleoside' named entity 'virus' named entity 'SARS-CoV' named entity 'crossed the species barrier' named entity 'antibodies' named entity 'nidovirus' named entity 'catalytic domain' named entity 'molecular mechanisms' named entity 'SARS-CoV' named entity 'cytoplasmic domain' named entity 'SARS-CoV' named entity 'protease'

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