About: Analysis of factors affecting the prognosis of COVID-19 patients and viral shedding duration

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Analysis of factors affecting the prognosis of COVID-19 patients and viral shedding duration
Creator	Xie, Yi Li, Jian-Guo Han, Jing Huang, Shu-Ping Shao, Shi-Feng Shi, Li-Xia Wang, He-Rong Zhang, Yong-Jin
Source	Medline; PMC
abstract	The clinical characteristics of patients with COVID-19 were analysed to determine the factors influencing the prognosis and virus shedding time to facilitate early detection of disease progression. Logistic regression analysis was used to explore the relationships among prognosis, clinical characteristics and laboratory indexes. The predictive value of this model was assessed with receiver operating characteristic curve analysis, calibration and internal validation. The viral shedding duration was calculated using the Kaplan–Meier method, and the prognostic factors were analysed by univariate log-rank analysis and the Cox proportional hazards model. A retrospective study was carried out with patients with COVID-19 in Tianjin, China. A total of 185 patients were included, 27 (14.59%) of whom were severely ill at the time of discharge and three (1.6%) of whom died. Our findings demonstrate that patients with an advanced age, diabetes, a low PaO(2)/FiO(2) value and delayed treatment should be carefully monitored for disease progression to reduce the incidence of severe disease. Hypoproteinaemia and the fever duration warrant special attention. Timely interventions in symptomatic patients and a time from symptom onset to treatment <4 days can shorten the duration of viral shedding.
has issue date	2020-06-25(xsd:dateTime)
bibo:doi	10.1017/s0950268820001399
bibo:pmid	32580792
has license	cc-by
sha1sum (hex)	6cede9ef28c9a7fb26b66ed14608a43aea42d485
schema:url	https://doi.org/10.1017/s0950268820001399
resource representing a document's title	Analysis of factors affecting the prognosis of COVID-19 patients and viral shedding duration
has PubMed Central identifier	PMC7332754
has PubMed identifier	32580792
schema:publication	Epidemiol Infect
resource representing a document's body	covid:6cede9ef28c9a7fb26b66ed14608a43aea42d485#body_text
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