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About:
Survey of Clinical Laboratory Practices for 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Survey of Clinical Laboratory Practices for 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea
Creator
Sung, Heungsup
Ki, Chang-Seok
Kim, Jae-Seok
Kim, Mi-Na
Lee, Hyukmin
Seong, Moon-Woo
Yong, Dongeun
Lee, Mi-Kyung
Choi, Jong-Rak
Kim, Jeong-Ho
Kim, Sinyoung
Lim, Yong
Kweon, Joo
source
Medline; PMC
abstract
BACKGROUND: It is crucial to understand the current status of clinical laboratory practices for the largest outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infections in the Republic of Korea to be well prepared for future emerging infectious diseases. METHODS: We conducted a survey of 49 clinical laboratories in medical institutions and referral medical laboratories. A short questionnaire to survey clinical laboratory practices relating to MERS-CoV diagnostic testing was sent by email to the directors and clinical pathologists in charge of the clinical laboratories performing MERS-CoV testing. The survey focused on testing volume, reporting of results, resources, and laboratory safety. RESULTS: A total of 40 clinical laboratories responded to the survey. A total of 27,009 MERS-CoV real-time reverse transcription PCR (rRT-PCR) tests were performed. Most of the specimens were sputum (73.5%). The median turnaround time (TAT) was 5.29 hr (first and third quartile, 4.11 and 7.48 hr) in 26 medical institutions. The median TAT of more than a half of the laboratories (57.7%) was less than 6 hr. Many laboratories were able to perform tests throughout the whole week. Laboratory biosafety preparedness included class II biosafety cabinets (100%); separated pre-PCR, PCR, and post-PCR rooms (88.6%); negative pressure pretreatment rooms (48.6%); and negative pressure sputum collection rooms (20.0%). CONCLUSIONS: Clinical laboratories were able to quickly expand their diagnostic capacity in response to the 2015 MERS-CoV outbreak. Our results show that clinical laboratories play an important role in the maintenance and enhancement of laboratory response in preparation for future emerging infections.
has issue date
2015-12-18
(
xsd:dateTime
)
bibo:doi
10.3343/alm.2016.36.2.154
bibo:pmid
26709263
has license
cc-by-nc
sha1sum (hex)
6db877f61327ae24341591d620abda3793639462
schema:url
https://doi.org/10.3343/alm.2016.36.2.154
resource representing a document's title
Survey of Clinical Laboratory Practices for 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea
has PubMed Central identifier
PMC4713849
has PubMed identifier
26709263
schema:publication
Ann Lab Med
resource representing a document's body
covid:6db877f61327ae24341591d620abda3793639462#body_text
is
schema:about
of
named entity 'PRACTICES'
named entity 'REPUBLIC OF KOREA'
named entity 'INFECTIONS'
named entity 'CURRENT'
named entity 'EMERGING INFECTIOUS DISEASES'
named entity 'BACKGROUND'
named entity 'LARGEST'
named entity 'UNDERSTAND'
named entity 'PREPARED'
named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS'
named entity 'CLINICAL LABORATORY'
named entity 'SURVEY'
named entity '2015'
named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS'
named entity 'FUTURE'
named entity 'OUTBREAK'
named entity 'OUTBREAK'
named entity 'PRACTICES'
named entity 'STATUS'
named entity 'CLINICAL LABORATORY'
named entity 'REPUBLIC OF KOREA'
covid:arg/6db877f61327ae24341591d620abda3793639462
named entity 'Republic of Korea'
named entity 'clinical laboratory'
named entity 'Republic of Korea'
named entity 'MERS-CoV'
named entity 'H1N1'
named entity 'Middle East respiratory syndrome coronavirus'
named entity 'MERS-CoV'
named entity 'emerging infections'
named entity 'MERS-CoV'
named entity 'rRT-PCR'
named entity 'rRT-PCR'
named entity 'rRT-PCR'
named entity 'sputum'
named entity 'MERS-CoV'
named entity 'MERS-CoV'
named entity 'clinical laboratories'
named entity 'public health laboratories'
named entity 'diagnostic testing'
named entity 'ECDC'
named entity 'European Centre for Disease Prevention and Control'
named entity 'H1N1'
named entity 'H1N1'
named entity 'MERS-CoV'
named entity 'emerging pathogens'
named entity 'H1N1'
named entity 'etiology'
named entity 'chi-square test'
named entity 'diagnostic tests'
named entity 'MERS-CoV'
named entity 'public health laboratories'
named entity 'molecular testing'
named entity 'standard precautions'
named entity 'United Arab Emirates'
named entity 'clinical pathologists'
named entity 'molecular diagnostic'
named entity 'lower respiratory tract'
named entity 'infection'
named entity 'virus'
named entity '57.7%'
named entity 'clinical laboratory'
named entity 'medical laboratories'
named entity 'clinical laboratories'
named entity 'medical laboratories'
named entity 'rRT-PCR'
named entity 'emerging infectious diseases'
named entity 'MERS-CoV'
named entity 'rRT-PCR'
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