About: COVID-19 bei hospitalisierten Kindern und Jugendlichen: Ein systematischer Review zu publizierten Fallserien (Stand 31.03.2020) und erste Daten aus Deutschland

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About: COVID-19 bei hospitalisierten Kindern und Jugendlichen: Ein systematischer Review zu publizierten Fallserien (Stand 31.03.2020) und erste Daten aus Deutschland Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19 bei hospitalisierten Kindern und Jugendlichen: Ein systematischer Review zu publizierten Fallserien (Stand 31.03.2020) und erste Daten aus Deutschland
Creator	Kinderheilkd, Monatsschr Hartmann, · Koletzko, Redaktion Lücke, München Mayatepek, Bochum Armann, · Berner, · Wagner, Düsseldorf Wirth, Aachen Zepp, Wuppertal Liese, · Streng, Mainz
Source	Medline; PMC
abstract	BACKGROUND: The clinical knowledge about the course, complications and treatment of COVID-19 in children and adolescents is so far limited. AIM: This systematic review summarizes the current scientific evidence regarding the clinical presentation of COVID-19 in hospitalized children based on available case series from China. In addition, first data from a nationwide pediatric hospital survey conducted by the German Society for Pediatric Infectious Diseases (DGPI) are presented. METHODS: This study evaluated 12 case series from China with 6–2143 children infected with SARS-CoV‑2, which were identified by a literature search in PubMed up to 31 March 2020. The database of the German nationwide DGPI COVID-19 survey was accessed on 6 April 2020. RESULTS: The median patient age in the case series was between 2 and 7 years and 18–45% were infants <1 year of age. The duration of hospital stay was 5–20 days. Most commonly reported symptoms were fever and cough; in 40–100% of cases involvement of the lower respiratory tract was reported, usually confirmed by computed tomography (CT). Severe and critical courses of disease were reported in up to 8% of the children including 2 fatalities. So far the German DGPI COVID-19 survey reported 33 hospitalized children up to 6 April 2020, mostly with upper airway infections. Of these children, 45% were infants and 32% had an underlying medical condition. So far 3 children (9%) needed admission to an intensive care unit. CONCLUSION: COVID-19 in hospitalized children usually presented as an uncomplicated febrile upper airway infection or mild pneumonia. Severe cases or fatalities rarely occurred in children. Information on neonates and children with underlying chronic conditions as well as on therapeutic and preventive measures are urgently needed.
has issue date	2020-04-21(xsd:dateTime)
bibo:doi	10.1007/s00112-020-00919-7
bibo:pmid	32317808
has license	no-cc
sha1sum (hex)	6dcd12da79ce8a86230cee244e358c5d081808a9
schema:url	https://doi.org/10.1007/s00112-020-00919-7
resource representing a document's title	COVID-19 bei hospitalisierten Kindern und Jugendlichen: Ein systematischer Review zu publizierten Fallserien (Stand 31.03.2020) und erste Daten aus Deutschland
has PubMed Central identifier	PMC7171916
has PubMed identifier	32317808
schema:publication	Monatsschr Kinderheilkd
resource representing a document's body	covid:6dcd12da79ce8a86230cee244e358c5d081808a9#body_text
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