About: Treating the Host Response to Ebola Virus Disease with Generic Statins and Angiotensin Receptor Blockers

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About: Treating the Host Response to Ebola Virus Disease with Generic Statins and Angiotensin Receptor Blockers Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Treating the Host Response to Ebola Virus Disease with Generic Statins and Angiotensin Receptor Blockers
Creator	Fedson, David Jacobson, Jeffrey Opal, Steven Rordam, Ole
Source	Medline; PMC
abstract	Treatments targeting the Ebola virus may eventually be shown to work, but they will not have an impact on overall Ebola mortality in West Africa. Endothelial dysfunction is responsible for the fluid and electrolyte imbalances seen in Ebola patients. Because inexpensive generic statins and angiotensin receptor blockers restore endothelial barrier integrity, they can be used to treat the host response in these patients. In Sierra Leone, approximately 100 Ebola patients were treated with this combination, and reports indicate that survival was greatly improved.
has issue date	2015-06-23(xsd:dateTime)
bibo:doi	10.1128/mbio.00716-15
bibo:pmid	26106080
has license	cc-by-nc-sa
sha1sum (hex)	6e4d9a7b61701ca9620df0205d89b7fb8c22f265
schema:url	https://doi.org/10.1128/mbio.00716-15
resource representing a document's title	Treating the Host Response to Ebola Virus Disease with Generic Statins and Angiotensin Receptor Blockers
has PubMed Central identifier	PMC4479704
has PubMed identifier	26106080
schema:publication	mBio
resource representing a document's body	covid:6e4d9a7b61701ca9620df0205d89b7fb8c22f265#body_text
is schema:about of	named entity 'HAVE' named entity 'SEEN' named entity 'ANGIOTENSIN RECEPTOR BLOCKERS' named entity 'SIERRA LEONE' named entity 'WORK' named entity 'IMPACT' named entity 'MORTALITY' named entity '100' named entity 'FLUID' named entity 'GENERIC' named entity 'restore' named entity 'treat' named entity 'integrity' named entity 'Virus' named entity 'TREATING' named entity 'TARGETING' named entity 'GENERIC' named entity 'ANGIOTENSIN RECEPTOR BLOCKERS' named entity 'IMPROVED' named entity 'APPROXIMATELY' named entity 'GREATLY' named entity 'HOST RESPONSE' named entity 'TREAT' named entity 'HOST RESPONSE' named entity 'RESPONSE TO' named entity 'EBOLA VIRUS DISEASE' named entity 'COMBINATION' named entity 'ENDOTHELIAL DYSFUNCTION' named entity 'TREATED WITH' named entity 'SURVIVAL' named entity 'USED' named entity 'EBOLA' named entity 'TREATMENTS' named entity 'STATINS' named entity 'THESE' named entity 'WEST AFRICA' named entity 'BUT' named entity 'ELECTROLYTE IMBALANCES' named entity 'STATINS' named entity 'REPORTS' named entity 'RESPONSIBLE' named entity 'PATIENTS' named entity 'ENDOTHELIAL' named entity 'OVERALL' named entity 'EBOLA VIRUS' named entity 'BARRIER INTEGRITY' covid:arg/6e4d9a7b61701ca9620df0205d89b7fb8c22f265 named entity 'statins' named entity 'targeting' named entity 'Because' named entity 'host response' named entity 'Generic' named entity 'Response' named entity 'Ebola' named entity 'Ebola' named entity 'statins' named entity 'Statins' named entity 'Ebola' named entity 'case fatality rate' named entity 'ARBs' named entity 'host response' named entity 'angiotensin receptor blockers' named entity 'generic drugs' named entity 'Sierra Leone' named entity 'Ebola virus disease' named entity 'host response' named entity 'Ebola virus disease' named entity 'endothelial cells' named entity 'ICU' named entity 'Office of National Security' named entity 'statins' named entity 'host response' named entity 'electrolyte abnormalities' named entity 'Ebola' named entity 'Ebola virus' named entity 'influenza' named entity 'Ebola' named entity 'viruses'

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