About: Covid-19 in Chile. The experience of a Regional reference Center. Preliminary report

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Covid-19 in Chile. The experience of a Regional reference Center. Preliminary report
Creator	Fica, Alberto Alvarez, Ignacia Blackburn, Eileen Cubillos, Alberto Delama, Ignacio Garrido, Pamela Grandjean, Juan Muñoz, Daniel Navarrete, Maritza Olivares, Felipe
source	MedRxiv
abstract	During the first pandemic wave Covid-19 reached Latin America cities. Aim: To report clinical features and outcomes associated to Covid-19 in a group of patients admitted during the first wave in a regional reference Center in southern Chile designated to severe and critical cases. Methods: Cases were identified by a compatible clinical picture associated to positive RT-PCR or serological testing. A standard protocol was applied. Results: 21 adult patients (20 diagnosed by PCR, one by serology) were admitted between epidemiological weeks 13 to 20, involving 8.8% of total regional cases. Hospitalization occurred at a median of 11 days after symptoms onset. Patients [≥]60 years old predominated (57.1%). Hypertension (61.9%), obesity (57.1%) and diabetes mellitus 2 (38.1%) were prevalent but 19% had no comorbid conditions nor were elderly. Two cases involved second-trimester pregnant women. Positive IgM or IgM/IgG results obtained by rapid serological testing were limited (19% at 1st week; 42.9% at 2nd week). Nine patients (42.9%, critical group) were transferred to ICU and connected to mechanical ventilation due to respiratory failure. By univariate analysis admission to ICU was significantly associated to tachypnea and higher plasmatic LDH values. One pregnant woman required urgent cesarean section given birth to a premature neonate without vertical transmission. Two patients died (in-hospital mortality 9.5%) and length of stay was equal or higher than 14 days in 57.9% of patients. Conclusion: In our regional Center, Covid 19 was associated to known risk factors, had a prolonged stay and in-hospital mortality. Tachypnea [≥]30/min is predictive of transfer to ICU.
has issue date	2020-06-16(xsd:dateTime)
bibo:doi	10.1101/2020.06.14.20130898
has license	medrxiv
sha1sum (hex)	6e693ab48f2100e7ff778991c179a3af0c87c466
schema:url	https://doi.org/10.1101/2020.06.14.20130898
resource representing a document's title	Covid-19 in Chile. The experience of a Regional reference Center. Preliminary report
resource representing a document's body	covid:6e693ab48f2100e7ff778991c179a3af0c87c466#body_text
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