About: Small non-coding RNAs-based bone regulation and targeting therapeutic strategies

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Small non-coding RNAs-based bone regulation and targeting therapeutic strategies
Creator	Yang, Ying Fang, Sijie
Source	Elsevier; Medline; PMC
abstract	Abstract Small non-coding RNAs, which are 20–25 nucleotide ribonucleic acids, have emerged as an important transformation in the biological evolution over almost three decades. microRNAs (miRNAs) and short interfering RNAs (siRNAs) are two significant categories of the small RNAs that exert important effects on bone endocrinology and skeletology. Therefore, clarifying the expression and function of these important molecules in bone endocrine physiology and pathology is of great significance for improving their potential therapeutic value for metabolism-associated bone diseases. In the present review, we highlight the recent advances made in understanding the function and molecular mechanism of these small non-coding RNAs in bone metabolism, especially their potentially therapeutic values in bone-related diseases.
has issue date	2017-11-15(xsd:dateTime)
bibo:doi	10.1016/j.mce.2016.11.018
bibo:pmid	27888003
has license	els-covid
sha1sum (hex)	6e7ca21e4d19e750e53bc58f099aac0dfd93198b
schema:url	https://doi.org/10.1016/j.mce.2016.11.018
resource representing a document's title	Small non-coding RNAs-based bone regulation and targeting therapeutic strategies
has PubMed Central identifier	PMC7116989
has PubMed identifier	27888003
schema:publication	Molecular and Cellular Endocrinology
resource representing a document's body	covid:6e7ca21e4d19e750e53bc58f099aac0dfd93198b#body_text
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