About: Evaluation of respiratory syncytial virus IgG antibody dynamics in mother-infant pairs cohort

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About: Evaluation of respiratory syncytial virus IgG antibody dynamics in mother-infant pairs cohort Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Evaluation of respiratory syncytial virus IgG antibody dynamics in mother-infant pairs cohort
Creator	Somer, Ayper Agacfidan, Ali Unuvar, Emin Mehmet, & Yildiz, Mehmet Coban, Asuman Demircili, Emin Kara, Manolya Mese, Sevim Selda, & Sivrikoz, Sarac Sutcu, Murat Torun, Hancerli Tugba, &
source	PMC
abstract	RSV is one of the most important agents of lower respiratory infections in childhood. In this study, anti-RSV antibody levels in mother-infant pairs and factors related to antibody transfer ratio were investigated. One hundred and twenty-seven women that had term babies and their babies and 84 mother-infant pairs of them who continued the study after 6 months were enrolled. Anti-RSV IgG antibodies of the mothers and infants were positive in 46.5% and 61.5%, respectively. At the sixth month, anti-RSV antibodies were negative in all infants. Median of the anti-RSV antibody levels of the mothers and infants at birth were 12.08 IU/ml (1.21–119.27) and 13.78 IU/ml (3.99–108.6), respectively. There was a significant correlation between anti-RSV antibody levels of mothers and infants at birth (p: 0.0001, r: 0.667) and anti-RSV antibody levels of infants at birth and at 6th month (p: 0.0001, r: 0.343). Median ratio of infant and mother antibody levels was 1.22 (0.14–6.05). Median ratio that was detected in appropriate for gestational age infants was significantly higher than in small for gestational age or large for gestational age infants. In this study, the significant positive correlation between maternal antibody levels and infants’ antibody levels at birth suggests that maternal vaccination strategies may be logical. We showed that antibody transfer rate was highest in appropriate for gestational age infants. It should be kept in mind that maternal vaccination strategies may be less effective in small for gestational age and large for gestational age infants.
has issue date	2020-02-14(xsd:dateTime)
bibo:doi	10.1007/s10096-020-03841-8
bibo:pmid	32060753
has license	no-cc
sha1sum (hex)	6f93af7555f41f174f4871c7147c8f4b90174275
schema:url	https://doi.org/10.1007/s10096-020-03841-8
resource representing a document's title	Evaluation of respiratory syncytial virus IgG antibody dynamics in mother-infant pairs cohort
has PubMed Central identifier	PMC7223508
has PubMed identifier	32060753
schema:publication	Eur J Clin Microbiol Infect Dis
resource representing a document's body	covid:6f93af7555f41f174f4871c7147c8f4b90174275#body_text
is schema:about of	named entity 'antibody' named entity 'antibody' named entity 'mind' named entity 'detected' named entity 'mothers' named entity 'antibodies' named entity 'gestational age' named entity 'correlation' named entity '28P' named entity 'MATERNAL' named entity 'HIGHER' named entity 'ONE OF' covid:arg/6f93af7555f41f174f4871c7147c8f4b90174275 named entity 'study' named entity 'pairs' named entity 'There' named entity 'levels' named entity 'pairs' named entity 'infants' named entity 'maternal' named entity 'logical' named entity 'babies' named entity 'antibody' named entity 'antibody' named entity 'large for gestational age' named entity 'antibody' named entity 'large for gestational age' named entity 'positive correlation' named entity 'infants' named entity 'antibody' named entity 'RSV' named entity 'antibody' named entity 'seropositivity' named entity 'Student's T test' named entity 'prospective studies' named entity 'RSV' named entity 'IgG antibody' named entity 'AGA' named entity 'respiratory syncytial virus' named entity 'Turkey' named entity 'low birth weight' named entity 'IgG antibody' named entity 'prematurity' named entity 'antibody' named entity 'statistically significant' named entity 'RSV' named entity 'Lower respiratory tract infections' named entity 'antibody' named entity 'AGA' named entity 'χ2 test' named entity 'IgG antibody' named entity 'pathologies' named entity 'weeks of gestation' named entity 'gestation' named entity 'public health' named entity 'Blood samples' named entity 'meta-analysis' named entity 'birth weight' named entity 'statistically significant' named entity 'birth weights' named entity 'morbidity rates' named entity 'IgG' named entity 'RSV' named entity 'antibody' named entity 'influenza virus' named entity 'morbidity' named entity 'RSV' named entity 'RSV'

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