About: N95 Mask Decontamination using Standard Hospital Sterilization Technologies

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	N95 Mask Decontamination using Standard Hospital Sterilization Technologies
Creator	Kumar, Anand Leung, Anders Cutts, Todd Zarychanski, Ryan Strong, James Hills, Kevin Kasloff, Samantha Krishnan, Jay Lother, Sylvain Rush, Barret Vazquez-Grande, Gloria
Source	MedRxiv
abstract	The response to the COVID19 epidemic is generating severe shortages of personal protective equipment around the world. In particular, the supply of N95 respirator masks has become severely depleted with supplies having to be rationed and health care workers having to use masks for prolonged periods in many countries. We sought to test the ability of 4 different decontamination methods including autoclave treatment, ethylene oxide gassing, ionized hydrogen peroxide fogging and vaporized hydrogen peroxide exposure to decontaminate 4 different N95 masks of experimental contamination with SARS-CoV-2 or vesicular stomatitis virus as a surrogate. In addition, we sought to determine whether masks would tolerate repeated cycles of decontamination while maintaining structural and functional integrity. We found that one cycle of treatment with all modalities was effective in decontamination and was associated with no structural or functional deterioration. Vaporized hydrogen peroxide treatment was tolerated to at least 5 cycles by masks. Most notably, standard autoclave treatment was associated with no loss of structural or functional integrity to a minimum of 10 cycles for the 3 pleated mask models. The molded N95 mask however tolerated only 1 cycle. This last finding may be of particular use to institutions globally due to the virtually universal accessibility of autoclaves in health care settings.
has issue date	2020-04-08(xsd:dateTime)
bibo:doi	10.1101/2020.04.05.20049346
has license	medrxiv
sha1sum (hex)	702ecc2703cdf910eb773274d93d00f17fd51a30
schema:url	https://doi.org/10.1101/2020.04.05.20049346
resource representing a document's title	N95 Mask Decontamination using Standard Hospital Sterilization Technologies
resource representing a document's body	covid:702ecc2703cdf910eb773274d93d00f17fd51a30#body_text
is schema:about of	named entity 'peroxide' named entity 'personal protective equipment' named entity 'experimental' named entity 'peroxide' named entity 'peroxide' named entity 'ADDITION' named entity 'UNIVERSAL' named entity 'MODALITIES' named entity 'N95 MASK' named entity 'DUE TO' named entity 'EPIDEMIC' named entity 'SARS-COV-2' named entity 'MODELS' named entity 'DECONTAMINATION' named entity 'AUTOCLAVE' named entity 'PERSONAL PROTECTIVE EQUIPMENT' named entity 'TREATMENT' named entity 'USE' named entity 'MAINTAINING' named entity 'METHODS' named entity 'SHORTAGES' named entity 'decontamination' named entity 'ability' named entity 'gassing' named entity 'institutions' named entity 'integrity' named entity 'generating' named entity 'Vaporized hydrogen peroxide' named entity 'vesicular stomatitis virus' named entity 'N95' named entity 'personal protective equipment' named entity 'VHP' named entity 'single-use' named entity 'VHP' named entity 'Rhabdoviridae' named entity 'VHP' named entity 'N95 masks' named entity 'respirator' named entity 'virus' named entity 'Minnesota' named entity 'VHP' named entity 'health care' named entity 'medRxiv' named entity 'protective gear' named entity 'Autoclaving' named entity 'VHP' named entity 'sterilize' named entity 'Irvine, California' named entity 'autoclaves' named entity 'respirator mask' named entity 'medRxiv' named entity 'vesicular stomatitis virus' named entity 'virus transmission' named entity 'loss of function' named entity 'St. Paul' named entity 'ethylene oxide' named entity 'autoclave' named entity 'COVID19' named entity 'health care' named entity 'carcinogenic' named entity 'streptomycin' named entity 'hydrogen peroxide' named entity 'virus' named entity 'Ethylene oxide' named entity 'health care' named entity 'SARS-CoV-2' named entity 'autoclaves' named entity 'N95 masks' named entity 'respirator' named entity 'Vesicular stomatitis virus' named entity 'N95 masks' named entity 'COVID-19' named entity 'autoclaving' named entity 'VHP' named entity 'Vero E6'

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