About: Emerging outbreaks associated with equine coronavirus in adult horses

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Emerging outbreaks associated with equine coronavirus in adult horses
Creator	Ball, R Bartol, J Burns, P Butterworth, K Magdesian, K Mapes, S Ormond, C Pusterla, N Sapp, K Wademan, C White, A
Source	Elsevier; Medline; PMC
abstract	The purpose of this study was to describe clinical, hematological and fecal PCR results from 161 horses involved in outbreaks associated with ECoV. The outbreaks happened at four separate boarding facilities between November 2011 and April 2012 in the States of CA, TX, WI and MA. Following the molecular detection of ECoV in the feces from the initial index cases, the remaining herdmates were closely observed for the development of clinical signs. Fecal samples were collected from sick and healthy horses for the PCR detection of ECoV. All four outbreaks involved primarily adult horses. Fifty-nine horses developed clinical signs with 12–16 sick horses per outbreak. The main clinical signs reported were anorexia, lethargy and fever. Four horses from 3 different outbreaks were euthanized or died due to rapid progression of clinical signs. The cause of death could not be determined with necropsy evaluation in 2 horses, while septicemia secondary to gastrointestinal translocation was suspected in 2 horses. Blood work was available from 10 horses with clinical disease and common hematological abnormalities were leucopenia due to neutropenia and/or lymphopenia. Feces were available for ECoV testing by real-time PCR from 44 and 96 sick and healthy horses, respectively. 38/44 (86%) horses with abnormal clinical signs tested PCR positive for ECoV, while 89/96 (93%) healthy horses tested PCR negative for ECoV. The overall agreement between clinical status and PCR detection of ECoV was 91%. The study results suggest that ECoV is associated with self-limiting clinical and hematological abnormalities in adult horses.
has issue date	2013-02-22(xsd:dateTime)
bibo:doi	10.1016/j.vetmic.2012.10.014
bibo:pmid	23123176
has license	no-cc
sha1sum (hex)	705cae38ab41bd310adebae3def2fd166aba31d3
schema:url	https://doi.org/10.1016/j.vetmic.2012.10.014
resource representing a document's title	Emerging outbreaks associated with equine coronavirus in adult horses
has PubMed Central identifier	PMC7117461
has PubMed identifier	23123176
schema:publication	Vet Microbiol
resource representing a document's body	covid:705cae38ab41bd310adebae3def2fd166aba31d3#body_text
is schema:about of	named entity 'ASSOCIATED WITH' named entity 'adult' named entity 'EQUINE CORONAVIRUS' named entity 'ADULT' named entity 'OUTBREAKS' named entity 'HORSES' named entity 'coronavirus' named entity 'ataxia' named entity 'coronavirus' named entity 'PCR' named entity 'Alphacoronavirus' named entity 'PCR' named entity 'Elsevier' named entity 'Japan' named entity 'Foster City' named entity 'maldigestion' named entity 'viruses' named entity 'supernatant' named entity 'quality control' named entity 'diarrhea' named entity 'real-time PCR' named entity 'uremia' named entity 'virus' named entity 'antigen-capture ELISA' named entity 'etiological agent' named entity 'Real-time PCR' named entity 'hematological' named entity 'neutropenia' named entity 'malabsorption' named entity 'mammalian species' named entity 'fever' named entity 'feces' named entity 'herpesvirus' named entity 'feces' named entity 'Oue' named entity 'gene' named entity 'clinical signs' named entity 'Betacoronavirus' named entity 'feces' named entity 'neurological disease' named entity 'clinical signs' named entity 'Betacoronavirus' named entity 'fever' named entity 'Hematological' named entity 'proximal' named entity 'self-limiting' named entity 'clinical presentation' named entity 'clinical signs' named entity 'bacteremia' named entity 'PCR' named entity 'hemagglutinating' named entity 'oligonucleotides' named entity 'molecular diagnostics' named entity 'coronaviruses' named entity 'Neorickettsia risticii' named entity 'leucopenia' named entity 'serological' named entity 'hematological' named entity 'feces' named entity 'gastrointestinal' named entity 'PCR' named entity 'equine' named entity 'Salmonella' named entity 'milliliters' named entity 'PCR' named entity 'rectal temperature' named entity 'necropsy' named entity 'HKU1' named entity 'feces' named entity 'suppurative' named entity 'neutropenia'

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