About: Etiology, seasonality, and clinical characterization of viral respiratory infections among hospitalized children in Beirut, Lebanon

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About: Etiology, seasonality, and clinical characterization of viral respiratory infections among hospitalized children in Beirut, Lebanon Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Etiology, seasonality, and clinical characterization of viral respiratory infections among hospitalized children in Beirut, Lebanon
Creator	Curran, Martin Afif, Claude El Jisr, Tamima Finianos, Mayda Hajj, Pierre Hakimeh, Noha Irani, Jihad Issa, Randi Naous, Amal Rajab, Maryam Chaar, Mira Hajj, Marie-Joelle
source	Medline; PMC
abstract	Acute respiratory tract viral infections occur worldwide and are one of the major global burdens of diseases in children. The aim of this study was to determine the viral etiology of respiratory infections in hospitalized children, to understand the viral seasonality in a major Lebanese hospital, and to correlate disease severity and the presence of virus. Over a 1‐year period, nasal and throat swabs were collected from 236 pediatric patients, aged 16‐year old or less and hospitalized for acute respiratory illness. Samples collected were tested for the presence of 17 respiratory viruses using multiplex real‐time RT‐PCR. Pathogens were identified in 165 children (70%) and were frequently observed during fall and winter seasons. Co‐infection was found in 37% of positive samples. The most frequently detected pathogens were human Rhinovirus (hRV, 23%), Respiratory Syncytial Virus (RSV, 19%), human Bocavirus (hBov, 15%), human Metapneumovirus (hMPV, 10%), and human Adenovirus (hAdV, 10%). A total of 48% of children were diagnosed with bronchiolitis and 25% with pneumonia. While bronchiolitis was often caused by RSV single virus infection and hAdV/hBoV coinfection, pneumonia was significantly associated with hBoV and HP1V1 infections. No significant correlation was observed between a single viral etiology infection and a specific clinical symptom. This study provides relevant facts on the circulatory pattern of respiratory viruses in Lebanon and the importance of using PCR as a useful tool for virus detection. Early diagnosis at the initial time of hospitalization may reduce the spread of the viruses in pediatric units. J. Med. Virol. 88:1874–1881, 2016. © 2016 Wiley Periodicals, Inc.
has issue date	2016-05-19(xsd:dateTime)
bibo:doi	10.1002/jmv.24544
bibo:pmid	27061822
has license	no-cc
sha1sum (hex)	70d6b5ab004ee880df76a4a88940945d16225155
schema:url	https://doi.org/10.1002/jmv.24544
resource representing a document's title	Etiology, seasonality, and clinical characterization of viral respiratory infections among hospitalized children in Beirut, Lebanon
has PubMed Central identifier	PMC7167081
has PubMed identifier	27061822
schema:publication	J Med Virol
resource representing a document's body	covid:70d6b5ab004ee880df76a4a88940945d16225155#body_text
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