About: Novel canine circovirus strains from Thailand: Evidence for genetic recombination

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About: Novel canine circovirus strains from Thailand: Evidence for genetic recombination Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Novel canine circovirus strains from Thailand: Evidence for genetic recombination
Creator	Osterhaus, Albert Baumgärtner, Wolfgang Ludlow, Martin Piewbang, Chutchai Techangamsuwan, Somporn Rungsipipat, Anudep Puff, Christina Jung, Klaus Kesdangsakonwut, Sawang Kruppa, Jochen Jo, Wendy Van Der Vries, Erhard
source	Medline; PMC
abstract	Canine circoviruses (CanineCV’s), belonging to the genus Circovirus of the Circoviridae family, were detected by next generation sequencing in samples from Thai dogs with respiratory symptoms. Genetic characterization and phylogenetic analysis of nearly complete CanineCV genomes suggested that natural recombination had occurred among different lineages of CanineCV’s. Similarity plot and bootscaning analyses indicated that American and Chinese viruses had served as major and minor parental viruses, respectively. Positions of recombination breakpoints were estimated using maximum-likelihood frameworks with statistical significant testing. The putative recombination event was located in the Replicase gene, intersecting with open reading frame-3. Analysis of nucleotide changes confirmed the origin of the recombination event. This is the first description of naturally occurring recombinant CanineCV’s that have resulted in the circulation of newly emerging CanineCV lineages.
has issue date	2018-05-14(xsd:dateTime)
bibo:doi	10.1038/s41598-018-25936-1
bibo:pmid	29760429
has license	cc-by
sha1sum (hex)	715063d01372186739566d9c343b16ebb45f32eb
schema:url	https://doi.org/10.1038/s41598-018-25936-1
resource representing a document's title	Novel canine circovirus strains from Thailand: Evidence for genetic recombination
has PubMed Central identifier	PMC5951951
has PubMed identifier	29760429
schema:publication	Sci Rep
resource representing a document's body	covid:715063d01372186739566d9c343b16ebb45f32eb#body_text
is schema:about of	named entity 'Thailand' named entity 'strains' named entity 'Evidence' named entity 'THAILAND' named entity 'CANINE CIRCOVIRUS' named entity 'GENETIC RECOMBINATION' named entity 'EVIDENCE FOR' named entity 'NOVEL' named entity 'STRAINS' named entity 'secondary structure' named entity 'Invitrogen' named entity 'post-mortem' named entity 'NGS' named entity 'lung tissue' named entity 'ethanol' named entity 'gene' named entity 'RNA' named entity 'dog' named entity 'Chulalongkorn University' named entity 'hybridization' named entity 'PCV2' named entity 'virus' named entity 'Thailand' named entity 'tonsil' named entity 'nucleotide' named entity 'laboratory investigations' named entity 'NGS' named entity 'Taq polymerase' named entity 'BCIP' named entity 'liver' named entity 'diethyl pyrocarbonate' named entity 'phylogenetic' named entity 'GenBank' named entity 'acetylation' named entity 'Suwon' named entity 'recombinant' named entity 'tracheobronchial lymph node' named entity 'respiratory disease' named entity 'genetic recombination' named entity 'paramyxoviruses' named entity 'autopsied' named entity 'tissue samples' named entity 'PCV2' named entity 'lung' named entity 'virus' named entity 'gene' named entity 'gene' named entity 'hybridization' named entity 'Viral' named entity 'recombinant' named entity 'molecular analyses' named entity 'MAFFT' named entity 'gene' named entity 'virological' named entity 'program 4' named entity 'Thermo Fisher' named entity 'genomes' named entity 'kidneys' named entity 'dog' named entity 'recombination' named entity 'St. Louis' named entity 'proteinase' named entity 'gene' named entity 'liver tissue' named entity 'Basel' named entity 'genomes' named entity 'nucleotide substitution' named entity 'Thailand' named entity 'RNA' named entity 'gene'

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