About: Evaluation of the phytoconstituents of Auricularia auricula-judae mushroom and antimicrobial activity of its protein extract

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About: Evaluation of the phytoconstituents of Auricularia auricula-judae mushroom and antimicrobial activity of its protein extract Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evaluation of the phytoconstituents of Auricularia auricula-judae mushroom and antimicrobial activity of its protein extract
Creator	Oli, Angus Al-Dahmoshi, Hussein Al-Khafaji, Noor Al-Mosawi, Reham An, Oli Anyigor Edeh, Peter Ekuma, Onyeukwu Ekuma, Uchechukwu Hom, Al-Dahmoshi Mbachu, Amara Mbachu, Nancy Nsk, Al-Khafaji Okezie, Moses Onyeukwu Ekuma, Uchechukwu Pa, Edeh Rm, Al-Mosawi Saki, Morteza
Source	Elsevier; Medline; PMC
abstract	INTRODUCTION: The growing resistance to antibiotics and the complexity of defeating multi-drug resistant bacteria have led to an increase in the search for novel and effective antimicrobials from various plants. This study aimed to determine the bioactive contents of Auricularia auricular-judae mushroom and evaluate the antimicrobial potential of its protein extract against some selected human bacterial and fungal pathogens which could serve as a lead to the discovery of new antimicrobial agents. METHODS: The constituents of the A. auricular-judae were evaluated by standard phytochemical analysis methods. The agar well diffusion, micro-broth dilution, and time-kill kinetic assays were used to determine the antimicrobial activity of the extracts against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, yeast (Candida albicans), and dermatophytic pathogens. RESULTS: The preliminary phytochemical analysis of the extracts revealed the presence of carbohydrate (43.15%; 38.30%) proteins (23.75%; 23.75%), flavonoids (1.20%; 0.80%), alkaloids (0.60%; 1.00%), Saponin (6.00%; 2.40% ), Tannin (1.65%; 1.57%), Cyanide (0.24%; 0.40%), Ash (12.40%; 10.40%), moisture (6.00%;6.00%), lipids( 6.00%;6.00%), and fiber (8.70%; 6.45%) for the Tris buffer and warm aqueous extracts, respectively. The Tris and warm aqueous protein extracts showed antimicrobial effects toward all the human bacterial pathogens and two fungal isolates. CONCLUSIONS: This study revealed the potential ability of A. auricula-judae for use as a herbal antimicrobial in the treatment of human bacterial and fungal pathogens.
has issue date	2020-07-29(xsd:dateTime)
bibo:doi	10.1016/j.eujim.2020.101176
bibo:pmid	32834875
has license	no-cc
sha1sum (hex)	715e0e9378ad4bb9ec2643aca2611922189fd99a
schema:url	https://doi.org/10.1016/j.eujim.2020.101176
resource representing a document's title	Evaluation of the phytoconstituents of Auricularia auricula-judae mushroom and antimicrobial activity of its protein extract
has PubMed Central identifier	PMC7388757
has PubMed identifier	32834875
schema:publication	Eur J Integr Med
resource representing a document's body	covid:715e0e9378ad4bb9ec2643aca2611922189fd99a#body_text
is schema:about of	named entity 'mushroom' named entity 'defeating' named entity 'antimicrobial' named entity 'ANTIBIOTICS' named entity 'HAVE' named entity 'POTENTIAL' named entity 'BACTERIA ' named entity 'led' named entity 'plants' named entity 'protein' named entity 'This' named entity 'study' named entity 'extract' named entity 'resistance to antibiotics' named entity 'antimicrobial agents' named entity 'drug resistant bacteria' named entity 'Antimicrobial' named entity 'Auricularia auricula-judae' named entity 'antimicrobial activity' named entity 'mushroom' named entity 'freezer' named entity 'broth' named entity 'Aspergillus niger' named entity 'Gram-positive bacteria' named entity 'antibiotics' named entity 'protein' named entity 'antiviral' named entity 'antimicrobials' named entity 'nutritional status' named entity 'mushroom' named entity 'significant difference' named entity 'flavonoids' named entity 'supernatants' named entity 'cartilaginous' named entity 'protein' named entity 'ATCC' named entity 'Agaricus mushroom' named entity 'peptides' named entity 'protein' named entity 'aseptically' named entity 'kinetics' named entity 'Dermatophytes' named entity 'phytochemical analysis' named entity 'protein' named entity 'increasing resistance' named entity 'sodium' named entity 'fluconazole' named entity 'Trametes elegans' named entity 'non-photosynthetic' named entity 'incubation' named entity 'phytochemical analysis' named entity 'alkaloids' named entity 'zone of inhibition' named entity 'cyanide' named entity 'Aspergillus tamarii' named entity 'infection' named entity 'ethanol' named entity 'protein' named entity 'auricula' named entity 'Erwinia herbicola' named entity 'protein' named entity 'Auricularia' named entity 'air-dried' named entity 'ciprofloxacin' named entity 'diffusion'

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