About: Human bocavirus in hospitalized children under 5 years with acute respiratory infection, São Paulo, Brazil, 2010

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About: Human bocavirus in hospitalized children under 5 years with acute respiratory infection, São Paulo, Brazil, 2010 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Human bocavirus in hospitalized children under 5 years with acute respiratory infection, São Paulo, Brazil, 2010
Creator	Figueiredo, Cristina Isabel De Oliveira, Maria Luchs, Adriana Silva, Patricia Afonso, Sardinha Aparecida, Margarete Borges Da Silva, Bernardes Corrêa, Katia Daniela, · De Paiva, Maria Figueiredo-Deceased, Cristina Maria, Ana Pinho, Benega Santos, Oliveira Sousa, Renato Terezinha, ·
Source	Medline; PMC
abstract	The aims of this study were to investigate the human bocavirus (HBoV) frequency and genotypes in hospitalized children <5 years presenting acute respiratory infections (ARI) within the São Paulo metropolitan area. Nasopharyngeal samples from 300 patients, previously screened for common respiratory viruses, were tested by qPCR for the NSP1 and NP-1 genes. The VP1/2 gene in positive samples was then amplified by PCR and sequenced. A total of 49 positive HBoV cases (16.3%; mean Ct value of 34.41) were detected with the mean age being 18.1 months (range 1 month to 5 years) and the median age being 1 year of age. Children aged between 0 and 12 months had higher detection rates of HBoV (69.4%; 34/49; mean Ct = 34.45) than children from other age groups (30.6%; 15/49; mean Ct = 34.34). No significant differences were observed between HBoV Ct levels and clinical illness. The occurrence was more frequently associated with fall (38.8%; 19/49) and spring (36.7%; 18/49). All 12 sequenced isolates were identified as HBoV-1, displaying minor genetic variation compared to the Swedish reference strains ST1 and ST2 (99.1–99.7% nt). The sole identification of HBoV-1 supports the hypothesis that this particular genotype is strongly related to ARI, and contributes to the role of this virus in the aetiology of respiratory diseases.
has issue date	2018-02-01(xsd:dateTime)
bibo:doi	10.1007/s00705-017-3694-5
bibo:pmid	29392492
has license	no-cc
sha1sum (hex)	716d82274bb0de3381b02bedabac49479cdf9f3d
schema:url	https://doi.org/10.1007/s00705-017-3694-5
resource representing a document's title	Human bocavirus in hospitalized children under 5 years with acute respiratory infection, São Paulo, Brazil, 2010
has PubMed Central identifier	PMC7087275
has PubMed identifier	29392492
schema:publication	Arch Virol
resource representing a document's body	covid:716d82274bb0de3381b02bedabac49479cdf9f3d#body_text
is schema:about of	named entity 'respiratory infections' named entity 'genes' named entity 'acute' named entity 'screened' named entity 'hospitalized' named entity 'acute respiratory infection' named entity '12 MONTHS' named entity 'AETIOLOGY' named entity 'QPCR' named entity '300' named entity 'MONTH' named entity 'AMPLIFIED' named entity 'PRESENTING' named entity 'PCR' named entity 'GENOTYPES' named entity 'COMPARED' named entity 'VIRUS' named entity 'ST2' named entity 'RELATED' named entity 'SAMPLES' covid:arg/716d82274bb0de3381b02bedabac49479cdf9f3d named entity 'STRAINS' named entity 'AGED' named entity '2899' named entity 'RESPIRATORY VIRUSES' named entity 'PREVIOUSLY' named entity 'DETECTED' named entity 'GENETIC VARIATION' named entity 'ROLE' named entity 'REFERENCE' named entity 'ASSOCIATED WITH' named entity 'ILLNESS' named entity 'GENE' named entity 'LEVELS' named entity 'TESTED' named entity 'DISPLAYING' named entity 'IDENTIFIED' named entity 'NP-1' named entity 'MINOR' named entity 'SPRING' named entity 'ISOLATES' named entity 'SOLE' named entity 'YEAR' named entity 'AGE GROUPS' named entity 'AIMS' named entity 'NSP1' named entity 'MEDIAN' named entity 'GENES' named entity 'YEARS' named entity 'GENOTYPE' named entity 'FREQUENTLY' named entity 'NASOPHARYNGEAL' named entity 'TO INVESTIGATE' named entity 'PATIENTS' named entity 'AGE' named entity 'TOTAL' named entity 'HIGHER' named entity 'RATES' named entity 'FALL' named entity 'MEAN' named entity 'VP1' named entity 'HOSPITALIZED CHILDREN' named entity 'ACUTE RESPIRATORY INFECTION' named entity 'YEARS' named entity 'ACUTE RESPIRATORY INFECTIONS' named entity 'SIGNIFICANT'

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