About: Human rhinoviruses: The cold wars resume

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Human rhinoviruses: The cold wars resume
Creator	Mackay, Ian
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Human rhinoviruses (HRVs) are the most common cause of viral illness worldwide but today, less than half the strains have been sequenced and only a handful examined structurally. This viral super-group, known for decades, has still to face the full force of a molecular biology onslaught. However, newly identified viruses (NIVs) including human metapneumovirus and bocavirus and emergent viruses including SARS-CoV have already been exhaustively scrutinized. The clinical impact of most respiratory NIVs is attributable to one or two major strains but there are 100+ distinct HRVs and, because we have never sought them independently, we must arbitrarily divide the literature's clinical impact findings among them. Early findings from infection studies and use of inefficient detection methods have shaped the way we think of ‘common cold’ viruses today. OBJECTIVES: To review past HRV-related studies in order to put recent HRV discoveries into context. RESULTS: HRV infections result in undue antibiotic prescriptions, sizable healthcare-related expenditure and exacerbation of expiratory wheezing associated with hospital admission. CONCLUSION: The finding of many divergent and previously unrecognized HRV strains has drawn attention and resources back to the most widespread and frequent infectious agent of humans; providing us the chance to seize the advantage in a decades-long cold war.
has issue date	2008-05-27(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2008.04.002
bibo:pmid	18502684
has license	no-cc
sha1sum (hex)	718061446bc31523ae2da98b4eb33f8c0294aff9
schema:url	https://doi.org/10.1016/j.jcv.2008.04.002
resource representing a document's title	Human rhinoviruses: The cold wars resume
has PubMed Central identifier	PMC7108405
has PubMed identifier	18502684
schema:publication	J Clin Virol
resource representing a document's body	covid:718061446bc31523ae2da98b4eb33f8c0294aff9#body_text
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