About: ABO polymorphism and SARS-CoV-2 infection

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About: ABO polymorphism and SARS-CoV-2 infection - a meta-analysis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	ABO polymorphism and SARS-CoV-2 infection - a meta-analysis
Creator	Boetto, Erik Fantini, Maria Golinelli, Davide Maietti, Elisa
source	MedRxiv
abstract	At present, existing evidence about the association between SARS-CoV-2 infection and ABO blood group polymorphism is preliminary and controversial. In this meta-analysis we investigate this association and determine SARS-CoV-2 positive individuals odds of having a specific blood group compared to controls. We performed a systematic search on MEDLINE and LitCovid databases for studies published through July 12, 2020. 7 studies met inclusion criteria for meta-analysis, including a total of 13 subgroups of populations (7524 SARS-CoV-2 positive cases and 2962160 controls). We analysed the odds of having each blood group among SARS-CoV-2 positive patients compared with controls. Random-effects models were used to obtain the overall pooled odds ratio (OR). Subgroup and sensitivity analyses were performed in order to explore the source of heterogeneity and results consistency. The results of our meta-analysis indicate that SARS-CoV-2 positive individuals are more likely to have blood group A (pooled OR 1.21; 95%CI: 1.08-1.37) and less likely to have blood group O (pooled OR 0.76, 95%CI: 0.66-0.87). Further studies are needed to investigate the mechanisms at the basis of this association, which may affect the kinetics of the pandemic according to the blood group distribution within the population.
has issue date	2020-07-17(xsd:dateTime)
bibo:doi	10.1101/2020.07.17.20155986
has license	medrxiv
sha1sum (hex)	71854e4f6ec7624ae15a36016e795a2dc80ecc0b
schema:url	https://doi.org/10.1101/2020.07.17.20155986
resource representing a document's title	ABO polymorphism and SARS-CoV-2 infection - a meta-analysis
resource representing a document's body	covid:71854e4f6ec7624ae15a36016e795a2dc80ecc0b#body_text
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