About: Age could be driving variable SARS-CoV-2 epidemic trajectories worldwide

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Age could be driving variable SARS-CoV-2 epidemic trajectories worldwide
Creator	Abu-Raddadid, Laith Ayoubid 1☯, Houssein Chemaitellyid, Hiam Makhoulid, Monia Mumtaz, Ghina Seedat, Shaheen
Source	Medline; PMC
abstract	Current geographic spread of documented severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections shows heterogeneity. This study explores the role of age in potentially driving differentials in infection spread, epidemic potential, and rates of disease severity and mortality across countries. An age-stratified deterministic mathematical model that describes SARS-CoV-2 transmission dynamics was applied to 159 countries and territories with a population ≥1 million. Assuming worst-case scenario for the pandemic, the results indicate that there could be stark regional differences in epidemic trajectories driven by differences in the distribution of the population by age. In the African Region (median age: 18.9 years), the median R(0) was 1.05 versus 2.05 in the European Region (median age: 41.7 years), and the median (per 100 persons) for the final cumulative infection incidence was 22.5 (versus 69.0), for severe and/or critical disease cases rate was 3.3 (versus 13.0), and for death rate was 0.5 (versus 3.9). Age could be a driver of variable SARS-CoV-2 epidemic trajectories worldwide. Countries with sizable adult and/or elderly populations and smaller children populations may experience large and rapid epidemics in absence of interventions. Meanwhile, countries with predominantly younger age cohorts may experience smaller and slower epidemics. These predictions, however, should not lead to complacency, as the pandemic could still have a heavy toll nearly everywhere.
has issue date	2020-08-20(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0237959
bibo:pmid	32817662
has license	cc-by
sha1sum (hex)	7203b80dba1e72a6e95ad2a8dc2955ed14e97242
schema:url	https://doi.org/10.1371/journal.pone.0237959
resource representing a document's title	Age could be driving variable SARS-CoV-2 epidemic trajectories worldwide
has PubMed Central identifier	PMC7444586
has PubMed identifier	32817662
schema:publication	PLoS One
resource representing a document's body	covid:7203b80dba1e72a6e95ad2a8dc2955ed14e97242#body_text
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