About: Respiratory viral infections within one year after pediatric lung transplant

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Respiratory viral infections within one year after pediatric lung transplant
Creator	Danziger-Isakov, L Liu, M Michaels, M Worley, S Arrigain, S Aurora, P Ballmann, M Boyer, D Conrad, C Eichler, I Elidemir, O Faro, A Goldfarb, S Mallory, G Mogayzel, P Parakininkas, D Sweet, S Visner, G V\|sner, G
Source	Medline; PMC
abstract	Abstract: To characterize epidemiology and risk factors for respiratory viral infections (RVI) in pediatric lung transplant recipients within the first post‐transplant year, a retrospective multicenter study of pediatric lung transplant recipients from 1988 to 2005 was conducted at 14 centers in the United States and Europe. Data were recorded for 1 year post transplant. Associations between RVI and continuous and categorical risk factors were assessed using Wilcoxon's rank‐sum and χ(2) tests, respectively. Associations between time to RVI and risk factors or survival were assessed by multivariable Cox proportional hazards models. Of 576 subjects, 79 subjects (14%) had 101 RVI in the first year post transplant. Subjects with RVI were younger than those without RVI (median ages 9.7, 13; P<0.01). Viruses detected included adenovirus (n=25), influenza (n=9), respiratory syncytial virus (n=21), parainfluenza virus (n=19), enterovirus (n=4), and rhinovirus (n=22). In a multivariable model for time to first RVI, etiology other than cystic fibrosis (CF), younger age, and no induction therapy were independently associated with risk of RVI. Cytomegalovirus serostatus and acute rejection were not associated with RVI. RVI was independently associated with decreased 12‐month survival (hazard ratio 2.6, 95% confidence interval 1.6–4.4). RVI commonly occurs after pediatric lung transplantation with risk factors including younger age and non‐CF diagnosis. RVI is associated with decreased 1‐year survival.
has issue date	2009-05-03(xsd:dateTime)
bibo:doi	10.1111/j.1399-3062.2009.00397.x
bibo:pmid	19422670
has license	no-cc
sha1sum (hex)	725312d9e4074072f5f1cb610510e18bd623b7ab
schema:url	https://doi.org/10.1111/j.1399-3062.2009.00397.x
resource representing a document's title	Respiratory viral infections within one year after pediatric lung transplant
has PubMed Central identifier	PMC7169860
has PubMed identifier	19422670
schema:publication	Transpl Infect Dis
resource representing a document's body	covid:725312d9e4074072f5f1cb610510e18bd623b7ab#body_text
is schema:about of	named entity '2009' named entity 'lung transplant' named entity 'ONE YEAR' covid:arg/725312d9e4074072f5f1cb610510e18bd623b7ab named entity 'All rights reserved' named entity 'Respiratory' named entity 'Respiratory' named entity 'pediatric' named entity 'Respiratory viral infections' named entity 'immunosuppressive' named entity 'enteroviruses' named entity 'study design' named entity 'Cary, North Carolina' named entity 'demographic data' named entity 'RVI' named entity 'RVI' named entity 'RVI' named entity 'RVI' named entity 'pediatric' named entity 'diagnostic methods' named entity 'lung transplantation' named entity 'Infection' named entity 'RVI' named entity 'lung transplantation' named entity 'RVI' named entity 'pathology' named entity 'risk of death' named entity 'Cox proportional hazards model' named entity 'older age' named entity 'lung transplantation' named entity 'Institutional Review Board' named entity 'CMV' named entity 'Lung Transplant' named entity 'lung transplantation' named entity 'RVI' named entity 'serostatus' named entity 'HSV' named entity 'Clinical evidence' named entity 'RVI' named entity 'viruses' named entity 'infection' named entity 'lung transplantation' named entity 'trachea' named entity 'Cytomegalovirus' named entity 'rhinovirus' named entity 'Vaccination' named entity 'Younger children' named entity 'pulmonary function test' named entity 'retrospective cohort study' named entity 'biopsy' named entity 'RVI' named entity 'Cox proportional hazards models' named entity 'risk factor' named entity 'RVI' named entity 'FEV' named entity 'lung transplantation' named entity 'lung transplant' named entity 'lumen' named entity 'risk factors' named entity 'lung transplant' named entity 'RVI' named entity 'RVI' named entity 'SAS Institute'

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