About: COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties

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About: COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties
Creator	Asif, Muhammad Saleem, · Hafiza, · Raghdaa, · Saadullah, · Yaseen, Sidra Zarzour, Al
Source	Medline; PMC
abstract	Coronavirus disease of 2019 (COVID-19) has emerged as a global health threat. Unfortunately, there are very limited approved drugs available with established efficacy against the SARs-CoV-2 virus and its inflammatory complications. Vaccine development is actively being researched, but it may take over a year to become available to general public. Certain medications, for example, dexamethasone, antimalarials (chloroquine/hydroxychloroquine), antiviral (remdesivir), and IL-6 receptor blocking monoclonal antibodies (tocilizumab), are used in various combinations as off-label medications to treat COVID-19. Essential oils (EOs) have long been known to have anti-inflammatory, immunomodulatory, bronchodilatory, and antiviral properties and are being proposed to have activity against SARC-CoV-2 virus. Owing to their lipophilic nature, EOs are advocated to penetrate viral membranes easily leading to membrane disruption. Moreover, EOs contain multiple active phytochemicals that can act synergistically on multiple stages of viral replication and also induce positive effects on host respiratory system including bronchodilation and mucus lysis. At present, only computer-aided docking and few in vitro studies are available which show anti-SARC-CoV-2 activities of EOs. In this review, role of EOs in the prevention and treatment of COVID-19 is discussed. A discussion on possible side effects associated with EOs as well as anti-corona virus claims made by EOs manufacturers are also highlighted. Based on the current knowledge a chemo-herbal (EOs) combination of the drugs could be a more feasible and effective approach to combat this viral pandemic. [Image: see text]
has issue date	2020-08-14(xsd:dateTime)
bibo:doi	10.1007/s10787-020-00744-0
bibo:pmid	32803479
has license	no-cc
sha1sum (hex)	7269117b84a91a52f5ce7bd335b967559962eaa6
schema:url	https://doi.org/10.1007/s10787-020-00744-0
resource representing a document's title	COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties
has PubMed Central identifier	PMC7427755
has PubMed identifier	32803479
schema:publication	Inflammopharmacology
resource representing a document's body	covid:7269117b84a91a52f5ce7bd335b967559962eaa6#body_text
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