About: The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome

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About: The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome
Creator	Chastre, Jean Combes, Alain Nieszkowska, Ania Trouillet, Jean-Louis Schmidt, Matthieu Luyt, Charles-Edouard Schmidt, M Bréchot, Nicolas Dupont, Hervé Lebreton, Guillaume Leprince, Pascal Ouattara, Alexandre Repesse, Xavier Rozé, Hadrien Zogheib, Elie Bréchot, Á Chastre, Á Combes, Á Dupont, Á Lebreton, G Leprince, Á Luyt, C.-E Nieszkowska, Á Ouattara, Á Repesse, Á Rozé, H Trouillet, J.-L Zogheib, E
topic	covid:730913e0ef72862f884eb8a2bade5ebd55688d95#this
source	PMC
abstract	PURPOSE: This study was designed to identify factors associated with death by 6 months post-intensive care unit (ICU) discharge and to develop a practical mortality risk score for extracorporeal membrane oxygenation (ECMO)-treated acute respiratory distress syndrome (ARDS) patients. We also assessed long-term survivors’ health-related quality of life (HRQL), respiratory symptoms, and anxiety, depression and post-traumatic stress disorder (PTSD) frequencies. METHODS: Data from 140 ECMO-treated ARDS patients admitted to three French ICUs (2008–2012) were analyzed. ICU survivors contacted >6 months post-ICU discharge were assessed for HRQL, psychological and PTSD status. RESULTS: Main ARDS etiologies were bacterial (45 %), influenza A[H(1)N(1)] (26 %) and post-operative (17 %) pneumonias. Six months post-ICU discharge, 84 (60 %) patients were still alive. Based on multivariable logistic regression analysis, the PRESERVE (PRedicting dEath for SEvere ARDS on VV-ECMO) score (0–14 points) was constructed with eight pre-ECMO parameters, i.e. age, body mass index, immunocompromised status, prone positioning, days of mechanical ventilation, sepsis-related organ failure assessment, plateau pressure andpositive end-expiratory pressure. Six-month post-ECMO initiation cumulative probabilities of survival were 97, 79, 54 and 16 % for PRESERVE classes 0–2, 3–4, 5–6 and ≥7 (p < 0.001), respectively. HRQL evaluation in 80 % of the 6-month survivors revealed satisfactory mental health but persistent physical and emotional-related difficulties, with anxiety, depression or PTSD symptoms reported, by 34, 25 or 16 %, respectively. CONCLUSIONS: The PRESERVE score might help ICU physicians select appropriate candidates for ECMO among severe ARDS patients. Future studies should also focus on physical and psychosocial rehabilitation that could lead to improved HRQL in this population. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00134-013-3037-2) contains supplementary material, which is available to authorized users.
has issue date	2013-08-02(xsd:dateTime)
bibo:doi	10.1007/s00134-013-3037-2
bibo:pmid	23907497
has license	no-cc
sha1sum (hex)	730913e0ef72862f884eb8a2bade5ebd55688d95
schema:url	https://doi.org/10.1007/s00134-013-3037-2
resource representing a document's title	The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome
has PubMed Central identifier	PMC7094902
has PubMed identifier	23907497
schema:publication	Intensive Care Med
resource representing a document's body	covid:730913e0ef72862f884eb8a2bade5ebd55688d95#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/730913e0ef72862f884eb8a2bade5ebd55688d95
is schema:about of	named entity 'body' named entity 'Future studies' named entity 'symptoms' named entity 'select' named entity 'membrane oxygenation' named entity 'study' named entity 'membrane oxygenation' named entity 'SEVERE ARDS' named entity '0.001' named entity 'CONCLUSIONS' named entity 'EVALUATION' named entity 'FOCUS' named entity 'MECHANICAL VENTILATION' named entity 'MORTALITY RISK' named entity 'FUTURE' named entity '140' named entity 'DEATH' named entity 'IMPROVED' named entity 'SIX MONTHS' named entity 'APPROPRIATE' named entity 'STUDY' named entity 'DAYS' named entity 'SYMPTOMS' named entity 'PRONE' named entity 'INITIATION' named entity 'REPORTED' named entity 'TREATED' named entity '5-6' named entity 'SELECT' named entity 'IMMUNOCOMPROMISED' named entity 'POINTS' named entity 'PARAMETERS' named entity 'LONG-TERM' named entity 'PLATEAU PRESSURE' named entity 'END-EXPIRATORY PRESSURE' named entity 'RESULTS' named entity 'AGE' named entity 'POST-TRAUMATIC STRESS DISORDER' named entity 'DATA' named entity 'ICU' named entity 'POST-OPERATIVE' named entity 'TO IDENTIFY' named entity 'ETIOLOGIES' named entity 'RESPIRATORY SYMPTOMS' named entity 'OUTCOMES' named entity 'PROFILE' named entity 'PUBLICATION' named entity 'PRESERVE' named entity 'ANALYSIS' named entity 'EXTRACORPOREAL MEMBRANE OXYGENATION' named entity 'POSITIONING' named entity 'BASED'

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